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EC number: 212-634-7 | CAS number: 834-12-8
- Life Cycle description
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- Endpoint summary
- Appearance / physical state / colour
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- Vapour pressure
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- Endpoint summary
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- Ecotoxicological Summary
- Aquatic toxicity
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- Short-term toxicity to fish
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- Endocrine disrupter testing in aquatic vertebrates – in vivo
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- Specific investigations
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- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
The exposure of soil to 28 kg ametryn/ha for 28 days did not show significant effects on soil nitrification, and neither 28 kg/ha for 28 days nor 20 kg ametryn/ha for 42 days showed significant adverse effects on soil respiration.
In general, based on phytotoxicity, plant height and dry weight, monocotyledons where less sensitive to the test substance than dicotyledons. For monocotyledons, the NOECs ranged between 0.4 to 0.05 lb active ingredient/acre (lb ai/a). For dicotyledons, the NOECs ranged between 0.2 to less than 0.006 lb ai/a.
Based on seedling emergence and growth, dicotyledons were less sensitive than monocotyledons. Onion (Allium cepa) was the only plant species to exhibit a germination dose response determined to correspond to a NOEC of 2 lb ai/a. Based on seedling growth, a dose response was determined for the dicotyledons between 2.25 x 1011 and 2478 lb ai/a, and for monocotyledons between 47.2 and 23 lb ai/a.
When tested according to the US Environmental Protection Agency Office of Pesticide Programs (EPA OPP) 71-4 (Avian Reproduction Test), the test substance was determined to possess a NOEC of 300 mg/kg diet for Bobwhite quail (Colinus virginianus) and Mallard duck (Anas platyrhynchos).
REACH Annex X 9.4.4 Long-term toxicity testing on invertebrates:
The CSR attached within this dossier indicates that the PNECsoil based on the equilibrium partitioning method is 0.00057 mg/kg and the regional PECsoil is 0.000000159 mg/kg dw. Thus, the PECsoil / PNECsoil ratio is less than 0.01. Therefore, according to both the general risk assessment scheme and the integrated testing strategy in Figures R.7.11-2 and R.7.11-3 of TGD 7c, no additional long-term toxicity testing for soil organisms needs to be done.
In accordance with column 2 of REACH Annex X, the long-term toxicity testing on invertebrates (required in section 9.4.4) does not need to be conducted as the chemical safety assessment according to Annex I indicates no need to investigate further the effects of the substance and/or degradation products on terrestrial organisms.
TDG 7c: Guidance on information requirements and chemical safety assessment Chapter R.7c: Endpoint specific guidance (November 2012; version 1.1)
REACH Annex X 9.4.6 Long-term toxicity testing on plants:
The CSR attached within this dossier indicates that the PNECsoil based on the equilibrium partitioning method is 0.00057 mg/kg and the regional PECsoil is 0.000000159 mg/kg dw. Thus, the PECsoil / PNECsoil ratio is less than 0.01. Therefore, according to both the general risk assessment scheme and the integrated testing strategy in Figures R.7.11-2 and R.7.11-3 of TGD 7c, no additional long-term toxicity testing for soil organisms needs to be done.
In accordance with column 2 of REACH Annex X, the long-term toxicity testing on plants (required in section 9.4.6) does not need to be conducted as the chemical safety assessment according to Annex I indicates no need to investigate further the effects of the substance and/or degradation products on terrestrial organisms.
TDG 7c: Guidance on information requirements and chemical safety assessment Chapter R.7c: Endpoint specific guidance (November 2012; version 1.1)
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