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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 2017-04-11 to 2017-07-04
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Deviations:
no
GLP compliance:
no
Type of method:
dynamic method
Remarks:
vapour-liquid equilibrium
Key result
Temp.:
20 °C
Vapour pressure:
1.58 hPa
Key result
Temp.:
25 °C
Vapour pressure:
2.17 hPa
Key result
Temp.:
50 °C
Vapour pressure:
9.05 hPa

Thermal Stability:

The test item in a closed glass crucible showed an exothermic effect in the temperature range of 220 – 350 °C, with maximum decomposition energy of approximately -260 J/g.

Dynamic method: Vapour-liquid equilibrium (VLE):

The vapour pressure was measured in the temperature range of 54.0 to 103.2 °C.

Table 1: Results of the dynamic method

No.

Temperature (°C)

Vapoure pressure (hPa)

Remark

1

45.9

7.2

measured up

2

77.4

34.9

measured up

3

88.1

54.8

measured up

4

92.1

64.8

measured up

5

95.7

74.8

measured up

6

99.0

84.5

measured up

7

97.3

79.5

measured down

8

94.0

69.4

measured down

9

81.7

42.1

measured down

From the measured data points of the vapour pressure curve the constants A, B and C of the Antoine equation was derived by regression (Microsoft Excel) of the data points to

A = 10.3628

B = -2393.25

C = 273.15

The vapour pressure of the test item was calculated by extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C, according to Regulation EC No. 440/2008 Method A.4.

Conclusions:
The vapour pressure of the test item was calculated by extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C, to be 1.58, 2.17 and 9.05 hPa, respectively.
Executive summary:

A study was conducted according to OECD Test Guideline 104, Regulation (EC) No 440/2008 method A.4 and OPPTS 830.7950 to determine the vapour pressure of the test item. Therefore the vapour pressure was measured in the temperature range of 45.9 to 99.0 °C. From the measured data points of the vapour pressure curve the constants A, B and C of the Antoine equation were derived by regression of the data points. The vapour pressure was calculated by extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C to be 1.58, 2.17, and 9.05 hPa, respectively.

Description of key information

The vapour pressure of the test item was calculated by extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C, to be 1.58, 2.17 and 9.05 hPa, respectively.

Key value for chemical safety assessment

Vapour pressure:
1.58 hPa
at the temperature of:
20 °C

Additional information

A study was conducted according to OECD Test Guideline 104, Regulation (EC) No 440/2008 method A.4 and OPPTS 830.7950 to determine the vapour pressure of the test item (2017). Therefore the vapour pressure was measured in the temperature range of 45.9 to 99.0 °C. From the measured data points of the vapour pressure curve the constants A, B and C of the Antoine equation were derived by regression of the data points. The vapour pressure was calculated by extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C to be1.58, 2.17, and 9.05 hPa, respectively.