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Physical & Chemical properties

Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 2017-05-15 to 2017-10-18
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Version / remarks:
2004
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
2.5
Temp.:
23.5 °C
pH:
7.6
Conclusions:
The partion coefficient of the test item at 23.5 °C at a pH of 7.6 was found to be 2.5.
Executive summary:

In a study according to OECD Guideline 107 (shake flask method), a partition coefficient (n-octanol/water) of log Pow = 2.5 was determined. The concentrations of the test item were measured by HPLC with UV-detection.

Description of key information

The partion coefficient of the test item at 23.5 °C at a pH of 7.6 was found to be 2.5.

Key value for chemical safety assessment

Log Kow (Log Pow):
2.5
at the temperature of:
23.5 °C

Additional information

In a study according to OECD Guideline 107 (shake flask method) and GLP, a partition coefficient (n-octanol/water) of log Pow = 2.5 was determined. The concentrations of the test item were measured by HPLC with UV-detection.