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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
surface tension
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because water solubility is below 1 mg/L at 20°C
Justification for type of information:
JUSTIFICATION FOR DATA WAIVING
The water solubility is 0.034 mg/L (after 72h, at 20 °C) (exp. result, see IUCLID section 4.8, Rheinchemie, 2016).
Cross-reference
Reason / purpose for cross-reference:
data waiving: supporting information
Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
2015-09-25
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
not specified
GLP compliance:
no
Type of method:
flask method
Key result
Water solubility:
0.034 mg/L
Temp.:
20 °C
pH:
>= 4.9 - <= 6.4
Remarks on result:
other: average of solubilities determined after 24, 48, and 72h shaking
Water solubility:
0.021 mg/L
Temp.:
20 °C
pH:
5.4
Remarks on result:
other: average of solubilities determined after 24h shaking
Water solubility:
0.039 mg/L
Temp.:
20 °C
pH:
6.4
Remarks on result:
other: average of solubilities determined after 48h shaking
Water solubility:
0.041 mg/L
Temp.:
20 °C
pH:
4.9
Remarks on result:
other: average of solubilities determined after 72h shaking
Conclusions:
The water solubility of the test item (CAS 73912-21-7) was determined according to OECD 105 with accetable restrictions, using the flask method, which may be considered as a scientifically reasonable approach, and hence the result of 0.034 mg/L at 20°C can be considered to be reliable. This value is below the limit value of 0.1 mg/L, leading to the classification of the test item as insoluble.
Executive summary:

The water solubility of 2,2'-methylenebis[6-cyclohexyl-p-cresol] was determined to be 0.034 mg/L at 20°C using the shake flask method according to OECD guideline 105 (no GLP).

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion