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EC number: 606-661-7
CAS number: 208709-55-1
All animals survived the observation period. Body weight development of the treated rabbits was inconspicuous.
No signs of clinical toxicity were detected. No signs of irritation were observed at the cornea or iris. All animals showed discharge (score 1) one hour after instillation of the test material. Furthermore, a yellowish discoloration of the hairs around the eyes was seen in all treated animals up to day 6 and 7 of the experimental part. No abnormalities were detected in the untreated eyes.
Eve irritation of all animals (mean score):
The purpose of this primary eye irritation assay was to provide information on possible health hazards in case of acute eye contact with a test material and serve as a rational basis for risk assessment to the eye irritating potential of the test item in man.
To test for eye irritation a test according to the OECD-Guidelines for Testing of Chemicals No. 405, the annex to Directive 92/69 EEC, and the recommendations of DRAIZE (1959) was performed.
No eye irritating potential could be detected, thus the test material should not be classified as eye irritant according to EU Regulation No. 1272/2008 (CLP).
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