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Administrative data

Endpoint:
flammable solids
Type of information:
experimental study
Adequacy of study:
key study
Study period:
26 February 2013 - 28 March 2013
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study has been performed in accordance with the UN MTC Part III § 33.2.1.4 Test N.1 and EC.A10 guideline and complied with the principles of GLP.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report date:
2013

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
other: UN ST/SG/AC.10/11/Rev.5: Recommendations on the Transport of Dangerous Goods, Manual of Tests and Criteria, Part III Paragraph 33.2.1.4 “ Test N.1: “Test method for readily combustible solids” (2009)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.10 (Flammability (Solids))
Version / remarks:
(2008)
Deviations:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
3-aminopyrazine-2-carboxylic acid
EC Number:
226-558-7
EC Name:
3-aminopyrazine-2-carboxylic acid
Cas Number:
5424-01-1
Molecular formula:
C5H5N3O2
IUPAC Name:
3-aminopyrazine-2-carboxylic acid
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder
Details on test material:
- Name of test material (as cited in study report): Amiloride Compound 5
- Description: Tan powder
- Storage condition of test material: In refrigerator (2-8°C) protected from light, desiccated
- Other: Reactive to light, moisture and oxygen

Results and discussion

Any other information on results incl. tables

The flame of the gas burner did ignite the test substance pile. The test substance melted, burned with an orange blue flame and turned into a black charred residue. White smoke was observed. After removal of the ignition source, the flame extinguished after 50 seconds and no propagation of combustion was observed.

Applicant's summary and conclusion

Interpretation of results:
other: 'not highly flammable' by ignition
Conclusions:
Amiloride Compound 5 was determined to be 'not highly flammable' by ignition in a GLP-compliant study performed in accordance with UN MTC Test N.1 and EC.A10.