Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin irritation / corrosion

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Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Justification for type of information:
For this substance no in-vivo data are available for skin irritation in experimental animals. However, there are reliable human data for skin irritation available. The assessment of the skin irritation potential of the substance will thus be based on the human data. For detailled information of human data see Iuclid section 7.10. Therefore, based on scientific facts which are based on human data and additionally due to animal welfare the realization of an in-vivo skin irritation study in experimental animals is unjustified.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017

Materials and methods

Test guideline
Qualifier:
no guideline available
Version / remarks:
see IUCLID section 7.10
Principles of method if other than guideline:
see IUCLID section 7.10
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
Methyl myristate
EC Number:
204-680-1
EC Name:
Methyl myristate
Cas Number:
124-10-7
Molecular formula:
C15H30O2
IUPAC Name:
methyl myristate
Details on test material:
No more detailas available, database match.

Test animals

Species:
other: human

Results and discussion

In vivo

Results
Irritation parameter:
other: see 7.10
Basis:
other: see 7.10
Time point:
other: see 7.10
Remarks on result:
other: see 7.10

Applicant's summary and conclusion