Registration Dossier
Registration Dossier
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EC number: 209-042-6 | CAS number: 553-54-8
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Description of key information
As lithium benzoate will readily dissociate in biological systems, assessments have been made on lithium and benzoate ions.
There is a lot of work on lithium and a key document that summarises effects of lithium on reproduction and development is published by the California EPA. This review document cites a number of primary research sources and concludes that lithium is not directly linked to fertility of developmental toxicity. Two key references have been cited in the dossier; one shows limited reduction in fertility at ca 400 mg/kg/day lithium and the second demonstrates no significant developmental toxicity at 400 mg/kg/day lithium carbonate (ca 16 mg/kg/day lithium)
Justification for classification or non-classification
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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