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Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

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Description of key information

Earthworm reproduction test (OECD 222): EC10 (reproduction): 228 mg/kg soil dw (BASF SE, 2013, report no. 68E0695/00G009)

Key value for chemical safety assessment

Long-term EC10, LC10 or NOEC for soil macroorganisms:
228 mg/kg soil dw

Additional information

Effects of 2,2'-dimethyl-4,4'-methylenebis(cyclohexylamine) (CAS 6864-37-5) on the reproducibility of earthworms (E. fetida) were studied in a GLP guideline study following OECD 222. Based on nominal concentrations, the EC10 for effects on reproduction was 228 mg/kg soil dw (95% CL: 115.6 / 450.8) (BASF, 2013; report No. 68E0695/00G009).