Registration Dossier

Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Documentation insufficient for assessment, does not meet important criteria of today standard methods

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1959
Report Date:
1959

Materials and methods

Principles of method if other than guideline:
BASF-Test, see details in remarks on material and methods
GLP compliance:
no
Remarks:
pre GLP-study

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
other: Lutrol
Doses:
no data
No. of animals per sex per dose:
21 animals (no gender stated)
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
ca. 47 mg/kg bw
Remarks on result:
other: original value: 50 µl/kg bw (conversion into mg/kg bw is based on the density d=0.94 g/cm3)
Mortality:
no data
Clinical signs:
no data
Body weight:
no data
Gross pathology:
no data

Applicant's summary and conclusion