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EC number: 251-394-8 | CAS number: 33145-10-7
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 25 July 2016 to 26 August 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Version / remarks:
- European Community (EC), EC no. 440/2008, Part A: Methods for the Determination of Physico-Chemical Properties, Guideline A.1: “Melting/Freezing Temperature”, Official Journal of the European Union no. L142, May 31, 2008.
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Version / remarks:
- Organization for Economic Co-operation and Development (OECD), OECD Guidelines for the Testing of Chemicals no. 102: "Melting Point / Melting Range", July 27, 1995.
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7200 (Melting Point / Melting Range)
- Version / remarks:
- United States Environmental Protection Agency (EPA), Product Properties Test Guidelines no. OPPTS 830.7200: "Melting Point/Melting Range", March 1998.
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- differential scanning calorimetry
- Specific details on test material used for the study:
- No further details specified
- Key result
- Melting / freezing pt.:
- 162 °C
- Atm. press.:
- 1 013.25 hPa
- Decomposition:
- no
- Sublimation:
- no
- Conclusions:
- The melting temperature of Lowinox® 22IB46 was determined at 162°C (435K) using DSC.
- Executive summary:
The purpose of the study was to determine the physico-chemical properties for Lowinox® 22IB46.
The melting temperature of the test item were determined using differential scanning calorimetry (DSC), in accordance with the following guidelines:
European Community (EC), EC no. 440/2008, Part A: Methods for the Determination of Physico-Chemical Properties, Guideline A.1: “Melting/Freezing Temperature”, Official Journal of the European Union no. L142, May 31, 2008.
Organization for Economic Co-operation and Development (OECD), OECD Guidelines for the Testing of Chemicals no. 102: "Melting Point / Melting Range", July 27, 1995.
United States Environmental Protection Agency (EPA), Product Properties Test Guidelines no. OPPTS 830.7200: "Melting Point/Melting Range", March 1998.
The melting temperature of Lowinox® 22IB46 was determined at 162°C (435K) using DSC.
Reference
Preliminary test
At approximately 70°C a mechanical shock was observed. This did not influence the measurement. From 200°C upwards the weight of the sample decreased significantly. At 272°C the sample weight had decreased by 25%.
After the experiment no test item was observed in the sample container.
Main study
One minor and one major endothermic peak between 125°C and 175°C were observed. The extrapolated onset temperature of the minor peak was 149.39°C. This signal was most probably linked to the presence of an impurity or another crystallographic species. The extrapolated onset temperature of the major peak was 162.17°C. Both effects were most likely obtained due to melting.
To investigate the melting peaks between 125°C and 175°C a repeated heating cycle was applied in the Experiment 2. A closed sample container was applied to investigate the endothermic peak between 250°C and 325°C.
With the first heating the extrapolated onset temperature of the melting peak was 149.39°C. The extrapolated onset temperature of the second peak was 162.29°C.
During cooling no effects were observed which were due to crystallization of the test item (results are archived in the raw data).
During the second heating a glass transition was observed between 25°C and 50°C. The inflection point of the glass transition was 40.53°C. An exothermic peak was observed between 50°C and 125°C. The effect was obtained due to cold crystallization of the test item.
The extrapolated onset temperature of the first (minor) melting peak was 159.82°C. The peak maximum of the second (major) melting peak was 163.85°C. The extrapolated onset and the peak maximum were not used for calculating the melting temperature, since it was obtained by melting of non-original test item.
The melting temperature was determined as the average melting temperature obtained from experiment 1 (162.17°C) and experiment 2 (162.29°C).
Description of key information
Key value determined in a GLP accredited laboratory study using DSC in accordance with EU Method A.1, OECD Guideline 102 and US EPA Procedure OPPT 830.7200.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 162 °C
Additional information
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