Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 09 June 2017 to 25 July 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
2009
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Version / remarks:
1996
Deviations:
no
GLP compliance:
yes
Type of method:
effusion method: isothermal thermogravimetry

Test material

Constituent 1
Chemical structure
Reference substance name:
Tributyl-2-thiourea
EC Number:
219-350-2
EC Name:
Tributyl-2-thiourea
Cas Number:
2422-88-0
Molecular formula:
C13H28N2S
IUPAC Name:
1,1,3-tributylthiourea
Test material form:
liquid
Details on test material:
- Name of test material (as cited in study report): Tri butyl thiourea
- Appearance: Clear pale to medium brown liquid
- Storage conditions: At room temperature

Results and discussion

Vapour pressureopen allclose all
Key result
Temp.:
20 °C
Vapour pressure:
0.001 Pa
Key result
Temp.:
25 °C
Vapour pressure:
0.003 Pa

Any other information on results incl. tables

Table: Results of the isothermal TGA analysis (test item)

 

Temperature
[°C]

Weight loss
[ug/min]

vT [g/cm2/h]

log vT

log PT

PT
[Pa]

70

2.63131

3.14 E-4

-3.50

0.57

3.7

 

2.14033

2.55 E-4

-3.59

0.46

2.9

80

7.74248

9.24 E-4

-3.03

1.16

14

 

6.64079

7.93 E-4

-3.10

1.08

12

90

20.8089

2.48 E-3

-2.60

1.70

50

 

17.5099

2.09 E-3

-2.68

1.61

40

100

49.2597

5.88 E-3

-2.23

2.17

1.5 E2

 

39.4479

4.71 E-3

-2.33

2.05

1.1 E2

 

Applicant's summary and conclusion

Conclusions:
The vapour pressure of the substance at 20°C was determined to be 1.4E-3 Pa.
The vapour pressure of the substance at 25°C was determined to be 3.4E-3 Pa.
Executive summary:

The vapour pressure of the substance was determined using the isothermal thermogravimetric effusion method in a GLP study according to EC A.4, OECD 104 and OPPTS 830.7950. A vapour pressure curve was constructed from duplicate measurements at 70°C, 80°C, 90°C and 100°C. The vapour pressure of the substance at 20°C and 25°C was determined by extrapolation to be 1.4E-3 and 3.4E-3 Pa, resp.