Registration Dossier
Registration Dossier
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EC number: 201-549-0 | CAS number: 84-65-1
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
Based on available data, Anthraquinone was absorbed from the gastrointestinal tract and distributed to tissues. No indication of Anthraquinone bioaccumulation was apparent in any tissue. The majority of the radiolabel was eliminated in the feces and the urine. At 96 hours after dosing, less than 5% of the administered dose remained in major tissues. Elimination of over 50% of the administered radioactivity was found in the feces. There seemed to be an extensive hepatic metabolism of Anthraquinone. Analysis of urine revealed the presence of 11 metabolites, with 1-hydroxyAnthraquinone and 2-hydroxy Anthraquinone being the major ones.
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