Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 201-549-0 | CAS number: 84-65-1
Developmental toxicity / teratogenicity
Administrative data
- Endpoint:
- developmental toxicity
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2023-2024
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- The performance of the study is delayed due to the internal circumstances. The study will be performed. Please, see all attached documents:
- the proposal of the contract with the laboratory BIONEEDS INDIA PRIVATE LIMITED
- the proposal of the study plan
- the communication with ECHA
Our company is also in the contact with the Czech national enforcement Authority (Česká inspekce životního prostředí) and coordinates further action with this Authority.
DEZA is now negotiating the contract with laboratory Bioneeds. Expected start of the study: May 2023. Available information attached to this endpoint
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 023
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 414 (Prenatal Developmental Toxicity Study)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Anthraquinone
- EC Number:
- 201-549-0
- EC Name:
- Anthraquinone
- Cas Number:
- 84-65-1
- Molecular formula:
- C14H8O2
- IUPAC Name:
- 9,10-dihydroanthracene-9,10-dione
- Test material form:
- solid: particulate/powder
- Details on test material:
- - Name of test material (as cited in study report): Anthraquinone
- Physical state: crystalline powder
- Analytical purity: 98,9% w/w
- Impurities (identity and concentrations):
- Lot/batch No.:
- Expiration date of the lot/batch:
- Storage condition of test material: The sample of the test substance has been stored in the box in original packaging at room temperature
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
Administration / exposure
- Route of administration:
- oral: gavage
Results and discussion
Results: maternal animals
Effect levels (maternal animals)
- Key result
- Remarks on result:
- other: the study will be performed
Results (fetuses)
Effect levels (fetuses)
- Key result
- Remarks on result:
- other: the study will be performed
Overall developmental toxicity
- Developmental effects observed:
- not specified
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
