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Reaction mass of 1,4-bis(methylamino)anthraquinone and 1,4-bis[(2-ethylhexyl)amino]anthraquinone and 1-[(2-ethylhexyl)amino]-4-(methylamino)anthraquinone and 9,10-Anthracenedione, 1,4-bis(pentylamino)-, branched and linear and 9,10-Anthracenedione, 1-(methylamino)-4-(pentylamino)-, branched and linear and 9,10-Anthracenedione, 1-[(2-ethylhexyl)amino]-4-(pentylamino)-, branched and linear
EC number: 911-360-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

PBT assessment
Administrative data
PBT assessment: overall result
- Name:
- Legal Entity Composition: C.I. Solvent Blue 98 (3Amine)
- Type of composition:
- legal entity composition of the substance
- State / form:
- solid: particulate/powder
- Reference substance:
- Legal Entity Composition: C.I. Solvent Blue 98 (3Amine)
- Reference substance:
- Legal Entity Composition: C.I. Solvent Blue 98 (3Amine)
- Reference substance:
- Legal Entity Composition: C.I. Solvent Blue 98 (3Amine)
- Reference substance:
- Legal Entity Composition: C.I. Solvent Blue 98 (3Amine)
- Reference substance:
- Legal Entity Composition: C.I. Solvent Blue 98 (3Amine)
- Name:
- Boundary Composition: C.I. Solvent Blue 98 (3Amine)
- Type of composition:
- boundary composition of the substance
- State / form:
- solid: particulate/powder
- Reference substance:
- Boundary Composition: C.I. Solvent Blue 98 (3Amine)
- Reference substance:
- Boundary Composition: C.I. Solvent Blue 98 (3Amine)
- Reference substance:
- Boundary Composition: C.I. Solvent Blue 98 (3Amine)
- Reference substance:
- Boundary Composition: C.I. Solvent Blue 98 (3Amine)
- Reference substance:
- Boundary Composition: C.I. Solvent Blue 98 (3Amine)
- Reference substance:
- Boundary Composition: C.I. Solvent Blue 98 (3Amine)
- PBT status:
- the substance is not PBT / vPvB
- Justification:
The available evidence on degradation, bioaccumulation potential, and toxicity for C.I. Solvent Blue 98 (3 Amine) indicates that the screening criteria for persistence (P) is met, the screening criteria for bioaccumulation potential (B) is not met, and the screening criteria for toxicity (T) is not met. Based on the information described below, the substance is not PBT nor vP/vB.
Persistence assessment:Each of the evaluated components of C.I. Solvent Blue 98 (3 Amine) were estimated to be not readily biodegradable based on the Biowin outputs (BIOWIN, v4.10). These estimations are deemed reliable because the estimated biodegradabilities of structural analogues agree well with existing experimental data. Based on screening level criteria, the test substance is considered persistent (P).
Bioaccumulation assessment:The predicted log (base 10) of the n-octanol/water partition coefficient forthe components of C.I. Solvent Blue 98 (3 Amine) ranges from 2.89 to 10.98. The empirical determination of the log Kow (based on the OECD 117 HPLC method) indicates a log Kow for the test substance (which is a multi-component substance) ranging from 6.01 to > 6.5. The bioaccumulation potential of C.I. Solvent Blue 98 (3 Amine) was assessed via an EpiSuite QSAR, and the predicted BCF (BCFBAF V3.01) for all of the evaluated components ranged from 9.2to 76.9 L/kg wet weight(i.e.Log BCF = 0.96 to 1.89). This indicates a low probability of the test material to bioconcentrate in fish. Furthermore,Based on the metabolism prediction by ADMET predictor, allcomponents will be metabolized to hydroxylated metabolites by human CYP 1A2 or CYP 3A4 or combination of human CYP 1A2 and CYP 3A4. The formed aldehyde will be further metabolized to the corresponding acid by aldehyde dehydrogenase (ALDH). The formed metabolites can also be further metabolized to water soluble metabolites (such as glucuronides and sulfates), which will be mainly excreted into urine and feces.Therefore on the basis of low volume of distribution as exemplified by the high empirical Log Kow values, and predicted metabolism and excretion of all components, it can be predicted that this substance is not likely to bioaccumulate. Thus, the test material is not expected to be bioaccumulative (B).
Toxicity assessment:The screening assessment for environmental toxicity is based on acute aquatic toxicity testing. No aquatic toxicity testing is available for C.I. Solvent Blue 98 (3 Amine) since the main components are highly water insoluble. To estimate acute aquatic toxicity, EPISUITE ECOSAR (v1.00) was conducted for the main components of C.I. Solvent Blue 98 (3 Amine). ECOSAR estimates indicated that acute toxicity is not expected at concentrations below the predicted water solubility limit for this material, with one minor exception where one modeled component indicated acute toxicity (i.e.96-hr EC50) to algae at a concentration of 26.5 mg/L. Furthermore, reproductive, genotoxicity and repeat dose toxicity studies exposing rats to C.I. Solvent Blue 98 (3 Amine) indicated no concerns for reproductive, mutagenic, or repeat dose toxicity, respectively. Thus C.I. Solvent Blue 98 (3 Amine) does not meet the criteria to be considered toxic (T).
Referenceopen allclose all
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