Reaction product of 2-Propenoic acid and Oxirane, mono[(C12-16-alkyloxy)methyl] derivs.

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

24 Jun - 28 Jun 2016

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Remarks:

The water solubility was determined based on total organic carbon (TOC) measurements.

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Version / remarks:

adopted in 2008

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: SANCO/3029/99 rev.4

GLP compliance:

yes (incl. QA statement)

Remarks:

LUBW Landesanstalt für Umwelt, Messungen un Naturschutz Baden-Württemberg, Karlsruhe, Germany

Type of method:

flask method

Specific details on test material used for the study:

Storage conditions: Ambient temperature (5 to 30 °C), in the dark, dry

Water solubility:

ca. 1.9 mg/L

Conc. based on:

test mat.

Temp.:

19.6 °C

pH:

ca. 6.13

Table 3 – Preliminary test results (first test)

Test item [mg]	Total volume of ultra-pure water [mL]	Time of shaking [min]	remarks	Approx.. solubility [g/L]
101.5	0.1	10	Not completely dissolved	< 1015
	0.5	10		< 203
	1	10		< 101.5
	2	10		< 50.8
	10	10		< 10.2
	100	10		< 1.0
	105	16 hours		< 1.0

 

Table 4 – Preliminary test results (second test)

Test item [mg]	Total volume of ultra-pure water [mL]	Time of shaking [min]	remarks	Approx.. solubility [g/L]
20	100	20	Not completely dissolved	< 200
	200	20		< 100
	300	20		< 66.7
	400	20		< 50
	500	20		< 40
	1000	16 hours	Not completely dissolved, emulsion	20

 

Table 5 – TOC Results

Sample code	TOC [mg/L]	TOCsample – TOCBlank [mg/L]
S16-03662 PTFE Blank  S16-03662 Flask 1 T120 S16-03662 Flask 1 T144 S16-03662 Flask 1 T168	0.65   1.8 2.0 2.1	/   1.15 1.35 1.45
Mean flask 1 Standard deviation [mg/L] Relative standard deviation [%]		1.32 mg/L TOC 0.15 11.4
S16-03662 Flask 2 T120 S16-03662 Flask 2 T144 S16-03662 Flask 2 T168	2.0 1.9 1.7	1.35 1.25 1.05
Mean flask 2 Standard deviation [mg/L] Relative standard deviation [%]		1.22 mg/L TOC 0.15 12.3
Mean Flask 1 and Flask 2 Deviation mean Flask 1 and mean Flask 2		1.27 mg/L TOC 8%

 

	TOC [%]
S16-03662 test item bulk material	68.2

 

Test item concentration calculation:

C(test item in sample) in mg/L

TOC(sample) in mg/L

TOC(test item) in %

C(test item in sample) = [TOC(sample) / TOC(test item)] x 100% = [1.27 mg/L / 68.2%] x 100% = 1.9 mg/L

Results display the required reproducibility (relative standard deviation is < 15%, deviation between the means of Flask 1 and Flask 2 is < 15%).

The water solubility of the test item was determined to be 1.9 mg/L in ultra-pure water at a temperature of 20 ± 0.5 °C and at a pH of 6.13.

Conclusions:

The water solubility was measured in accordance to OECD 105 and concluded to be 1.9 mg/L at 20 °C

Executive summary:

The water solubility was measured in accordance to OECD 105 and concluded to be 1.9 mg/L at 20 °C

Key value for chemical safety assessment

Water solubility:

1.9 mg/L

at the temperature of:

20 °C

Additional information

The water solubility was measured in accordance to OECD 105.