Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-969-4 | CAS number: 90-15-3
Measured Concentrations of A017 During the 48-Hour Static, Acute Toxicity
Test with Daphniamagna
Measured Concentration as mg A017/L(Percent Nominal)
*MQL = Minimum Quantifiable Limit
Immobility of Daphnia magna Exposed to A017 for 48 Hours Under Static Test Conditions
Cumulative Percent Immobile
Note: Five daphnids were placed in each replicate at test initiation, totaling 20 daphnids per treatment.
* Statistically significant reduction in survival as compared to the control (Fisher’s One-Tailed Exact Test, p < 0.05)
The acute toxicity of the test item to Daphnia magna was tested according to the OECD guideline 202 and GLP. The study was conducted under static conditions. 20 daphnies were exposed during the 48-hour exposure to the following mean measured concentrations 0.466, 0.793, 1.68, 3.27, and 6.51 mg /L, determined by High Performance Liquid Chromatography with ultraviolet detection (HPLC-UV) system. These measured concentrations represent recoveries of 99 to 117% of the nominal concentrations.
The water quality parameter (pH, oxygen) measured at the start and at the end of exposure were within the acceptable limits. The validity criteria of the guideline were fulfilled.
The EC50 on Daphnia magna after 48 h of exposure to the test item is 2.51 mg/L (95% confidence limit = 2.29 - 2.75 mg/L) expressed as mean measured concentration. The 48h-NOEC is 1.68 mg/L (mean measured concentration).
The EC50 on Daphnia magna after 48 h of exposure to the substance 1-naphtol (A017) under static conditions is 2.51 mg/L (95% confidence limit : 2.29 - 2.75 mg/L) expressed as mean measured concentration. The 48h-NOEC is 1.68 mg/L (mean measured concentration).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Close Do not show this message again