Benzenesulfonic acid, mono- and dialkylation products with C16-20 (even numbered, branched and linear) olefins, calcium salts, calcium carbonate, overbased, including distillates (petroleum), hydrotreated, solvent-refined, solvent-dewaxed, or catalytic dewaxed, light or heavy paraffinic C15-C50

Bioaccumulation: aquatic / sediment

Administrative data

Endpoint:

bioaccumulation in aquatic species: fish

Type of information:

migrated information: read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Data from a robust study summary included in an HPV Chemical Challenge document, April 2008; actual study report not reviewed, not known whether the study was conducted under GLP or not.

Data source

Reference

Reference Type:

publication

Title:

High Production Volume (HPV) Chemical Challenge Program: Final Revised Test Plan & Assessment with Robust Study Summaries fir Linear Alkylbenzene Sulfonic Acids & Derivatives, Part II: Robust Study Summaries for the LAS/ABS Category

Author:

The Soap & Detergent Association (SDA)

Year:

2008

Bibliographic source:

Kimerle, R.A., Macek, K.J., Sleight, B.H. and Burrows, M.E. 1981. Biococentration of linear alkylbenzene sulfonate (LAS) in bluegill (Lapomis macrochirus), Water Research, 15:251-256/U.S. EPA Chemical Assessment & Management Program Submissions

Materials and methods

Principles of method if other than guideline:

N/A

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

86411-30-3

IUPAC Name:

86411-30-3

Details on test material:

C10-13 LAS (CAS #68411-30-3) with the following alkyl chain
length distribution: C11 45%, C12 36.5%, C13 18.5%. Average
chain length was 11.7 and molecular weight was 344.

Radiolabelling:

yes

Sampling and analysis

Details on sampling:

Water samples were removed periodically for radiometric analysis
of 14C-labeled LAS. Four fish were removed on each of days 1, 2,
3, 5, 7, 9, 11 and 14 for radiometric analysis.

Test organisms

Test organisms (species):

Lepomis macrochirus

Details on test organisms:

Bluegill sunfish (avg wt. 4.0 g; avg length 68 mm) were placed in a
60 liter aquarium (375 fish total) and maintained for 21 days. A
second aquarium held 100 control fish. Fish were fed daily with a
dry pelleted trout chow ration of approximately 2% of body weight.

Study design

Test type:

flow-through

Total exposure / uptake duration:

21 d

Test conditions

Test temperature:

17+/- 1C

Nominal and measured concentrations:

0.5 mg/L

Results and discussion

Bioaccumulation factor

Remarks on result:

other: BCF104

Applicant's summary and conclusion

Conclusions:

The whole body BCF was measured as 104

Executive summary:

The bioconcentration of CASRN 68411 -30 -3, a structural analog of the target substance was measured in a flow-through study on Lepomis macrochirus. The study was carried out for 21 days at 17 +/- 1 C, and included an elimination phase. The test substance was C14 -labeled LAS. The whole-bosy BCF was determined to be 104. Basde on the result, the TS is also not expected to be bioaccumulative.

Ref: http://www.epa.gov/opptintr/chemrtk/pubs/summaries/alkybenz/c14187rt.pdf.