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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2005
Report date:
2005

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 201 (Alga, Growth Inhibition Test)
Deviations:
no
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
2-ethylphenol
EC Number:
201-958-4
EC Name:
2-ethylphenol
Cas Number:
90-00-6
Molecular formula:
C8H10O
IUPAC Name:
2-ethylphenol
Constituent 2
Chemical structure
Reference substance name:
4-ethylphenol
EC Number:
204-598-6
EC Name:
4-ethylphenol
Cas Number:
123-07-9
Molecular formula:
C8H10O
IUPAC Name:
4-ethylphenol
Constituent 3
Chemical structure
Reference substance name:
3-ethylphenol
EC Number:
210-627-3
EC Name:
3-ethylphenol
Cas Number:
620-17-7
Molecular formula:
C8H10O
IUPAC Name:
3-ethylphenol
Test material form:
not specified

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum)

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
72 h

Test conditions

Reference substance (positive control):
yes

Results and discussion

Effect concentrationsopen allclose all
Key result
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
> 22 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Key result
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
5.2 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
Since no concentration tested resulted in >=50% inhibition, the 72h EC50 was empirically estimated to be > 22 mg/L, the highest mean measured concentration tested. The 72h NOEC was determined to be 5.2 mg/L.