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EC number: 290-690-1
CAS number: 90218-17-0
EC50 (48h, Daphnia magna)
> 100 mg/L (nominal)
The following data was obtained for
the Similar Substance 01. It is expected that the Target substance will
present similar effect levels to daphnia. Justification for the use of a
read-across approach is provided in Section 13 of IUCLID.
The acute toxicity of the test item
to Daphnia magna under static conditions was investigated in an
experimental study, according to the OECD Guideline 202 screening test
(2004). Groups of 40 Daphnia magna (20 per tank) were exposed to
test item concentrations of 1 mg/L (low-concentration group), 10 mg/L
(mid-concentration group) and 100 mg/L (high concentration group) for a
duration of 48 hours. Daphnia were monitored for immobility at 24 and 48
hours. A negative control group of 60 Daphnia (20 per tank) were tested
No immobilisation was observed in
control or treatment tanks after 24 hours. After 48 hours, the three
control groups experienced 5 %, 10 % and 5 % immobilisation; 5 % and 10
% immobilisation occurred in groups exposed to 1 mg/L and 10 mg/L; 20 %
immobilisation occurred in the groups exposed to 100 mg/L. No analytical
measurement of test item concentration was performed throughout the
test. Based on Daphnia immobilisation, the 48-hour EC50value
was found to be greater than 100 mg/L based on nominal concentrations.
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