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Physical & Chemical properties

Water solubility

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Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 22 May 2012 to 20 December 2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
yes
Type of method:
flask method
Key result
Water solubility:
>= 1.604 other: g/ml
Temp.:
20 °C
pH:
0

Preliminary test results:

During the preliminary test, 0.1 mL of purified reagent water, when added carefully to 0.1024 g of test item, wholly dissolved into the acid. The resulting solution was clear and transparent. The mixture was observed to have no visible separation. The pH was tested using pH paper and was determined to be 0. Because there was no visible separation, the mixture was not observed after 24 hours.

Definitive test results:

The observations made in the definitive test are shown in the folloing table:

 

Observations

Amount of Test item

(g)

Total Volume of Test item (mL) added to 1 ml of water (mL)

0.1

0.5

0.75

1.0

1.6040

Clear; no visible layers

Clear; no visible layers

Clear; no visible layers

Clear; no visible layers

 

Amount of Test item Added (g)

0.1660

0.6367

0.4016

0.3997

Since the test substance is miscible in water, observations were made after the sample was added. If the test substance was found to be soluble, more test material was added (the additional test substance was weighed and recorded in order to determine total weight of test substance added). The solution was then shaken for 10 minutes and found to have no undissolved test material. 

The definitive test demonstrated the immediate and thorough dissolution of test item into water. Incremental additions of the test

material, for a total of 1.6040 g (1 mL) to 1.0 mL of purified reagent water, each dissolved, forming a clear homogenous solution.  The visual observations made during the preliminary and definitive test demonstrate that the test substance is freely miscible in purified reagent water. The results of this study demonstrate that test item completely dissolves in purified reagent water at a ratio of 1.6040 g of test item to 1.0 mL of purified reagent water. 

Conclusions:
Interpretation of results (migrated information): soluble (1000-10000 mg/L)
The water solubility of the test item at 20°C was >= 1.6040 g/ml. The test item is considered as soluble in water.
Executive summary:

The water solubility was determined by Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995 and GLP. No deviation from the Guidelines was observed during the test.

The solubility of a solid or liquid chemical can be defined as the maximum amount of the chemical (the solute) in solution at equilibrium with excess chemical present at specific conditions (temperature and atmospheric pressure). The water solubility of a substance is specified by the saturation mass concentration of the substance in water and is a function of temperature. 

The visual observations made during the preliminary and definitive test demonstrate that the test item is freely miscible in water. The results of incremental additions of the test material to purified reagent water demonstrate that the test item completely dissolved in purified reagent water at a ratio of 1.6040 g of test item to 1.0 mL of purified reagent water. The test item is considered as soluble in water.

Endpoint:
water solubility
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Justification for type of information:
The read-across justification is provided in the attached document.
Reason / purpose for cross-reference:
read-across source
Key result
Water solubility:
>= 1 604 g/L
Temp.:
20 °C
Remarks on result:
other: By analogy with the hydrolysis product
Conclusions:
By analogy with its degradation product in water, the water solubility of trifluoromethanesulfonic anhydride is considered to be above 1604 g/L at 20°C.
Endpoint:
water solubility
Data waiving:
study technically not feasible
Justification for data waiving:
the study does not need to be conducted because the substance is hydrolytically unstable at pH 4, 7 and 9 (half-life less than 12 hours)

Description of key information

Trifluoromethanesulfonic anhydride is rapidly hydrolysed in water, therefore it is not technically possible to measure a water solubility for this substance. The water solubility of the degradation product, i.e. trifluoromethanesulfonic acid, is considered as relevant for the assessment of trifluoromethanesulfonic anhydride.

The experimental determination of water solubility of trifluoromethanesulfonic acid was performed according to OECD TG 105 and GLP. The water solubility of the test item was found to be >= 1.6040 g/mL at 20°C.

Key value for chemical safety assessment

Water solubility:
1 604 g/L
at the temperature of:
20 °C

Additional information