Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
basic toxicokinetics, other
Remarks:
assessment
Type of information:
other: Expert judgement
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Expert judgement
Justification for type of information:
There is no specific requirement to generate toxicokinetic information in the REACH Regulation (EC 1907/2006). As reported in the Annex VIII, it is required to perform an assessment of the toxicokinetic behaviour of the substance to the extent that can be derived from the relevant available information.

Data source

Materials and methods

Objective of study:
other: Assessment
Principles of method if other than guideline:
Assessment
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Chlorphenesin
EC Number:
203-192-6
EC Name:
Chlorphenesin
Cas Number:
104-29-0
Molecular formula:
C9H11ClO3
IUPAC Name:
3-(4-chlorophenoxy)propane-1,2-diol
Test material form:
solid: particulate/powder

Results and discussion

Preliminary studies:
Assessment

Toxicokinetic / pharmacokinetic studies

Details on absorption:
Assessment
Details on distribution in tissues:
Assessment
Details on excretion:
Assessment

Metabolite characterisation studies

Details on metabolites:
Assessment

Bioaccessibility (or Bioavailability)

Bioaccessibility (or Bioavailability) testing results:
Assessment

Any other information on results incl. tables

Assessment.

Applicant's summary and conclusion

Conclusions:
General assessment.
Executive summary:

General assessment.

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