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EC number: 200-115-8 | CAS number: 51-67-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Appearance:
Chemical 4-(2-aminoethyl) phenol physically appear as a crystalline solid.
Melting point:
Melting point of chemcial 4-(2-aminoethyl) phenol is determine in the range between 164-165 Deg C.
Boiling Point:
Boiling point of chemcial 4-(2-aminoethyl) phenol is determine in the range between 205-207 Deg C at pressure 25 mmHg.
Density:
Density of chemical 4-(2-aminoethyl) phenol is determine to be 1.0630 g/cm3 at temperature 20 Deg C.
Particle size distribution:
The particle size distribution of 4-(2-aminoethyl)phenol was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 150 micron to 53 micron.
Vapour pressure:
The estimated vapour pressure of 4-(2-aminoethyl) phenol at temperature 25 deg C was 0.4226 Pa
Partition coefficient:
Based on the available data from authoritative and modelling databases, the partition coefficient (log Pow) value of the substance 4 -(2 -Aminoethyl)phenol was estimated to be 0.86. Based on this value, chemical 4 -(2 -Aminoethyl)phenol can be considered to be hydrophilic in nature.
Water solubility:
Water solubility of chemical 4-(2-aminoethyl) phenol is determine to be 10400 mg/L at temperature 15 Deg C. From this solubility value it is concluded that chemical 4-(2-aminoethyl) phenol is very soluble in water.
Surface tension:
In accordance with column 2 of Annex VII of the REACH regulation, the study need only be conducted if surface activity is a desired property of the chemical. 4-(2-Aminoethyl)phenol (CAS no. 51-67-2) is used as a flavoring agents. For this use, surface activity is not an important property. Hence this study was considered for waiver.
Flash point:
The study does not need to be conducted because the flash point is only relevant to liquids and low melting point solids.
Auto flammability:
4-(2-aminoethyl)phenol did not catch fire on being exposed to air at room temperature of 27°Cpressure of 966 hPa. This indicates that 4-(2-aminoethyl)phenol is not auto-flammable.
Flammability:
4-(2-aminoethyl)phenol does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 4-(2-aminoethyl)phenol is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 4-(2-aminoethyl)phenol was considered non-flammable.
Explosiveness:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties.
Oxidizing properties:
The study does not need to be conducted because the substance is a solid.
Additional information
Appearance:
Chemical 4-(2-aminoethyl) phenol physically appear as a crystalline solid.
From other reliable sources & authoritative databases it is concluded that chemical 4 -(2 -aminoethyl) phenol appear as a solid having pellets or needles.
Melting point:
Melting point of chemcial 4-(2-aminoethyl) phenol is determine in the range between 164-165 Deg C.
From other reliable sources & authoritative datbases it is concluded that melting point of chemcial 4 -(2 -aminoethyl) phenol is in the range between 161-165 Deg C.
Boiling Point:
Boiling point of chemcial 4-(2-aminoethyl) phenol is determine in the range between 205-207 Deg C at pressure 25 mmHg.
From other reliable sources & authorative databases it is concluded that boiling point of chemcial 4 -(2 -aminoethyl) phenol is to be 206 Deg C at pressure 25 mmHg & 175 -181 Deg C at pessure 8 mmHg & 166 Deg C at pressure 2 mmHg.
Density:
Density of chemical 4-(2-aminoethyl) phenol is determine to be 1.0630 g/cm3 at temperature 20 Deg C.
From other reliable sources & authoritative databases it is concluded that density of chemical 4 -(2 -aminoethyl) phenol is 1.0545 g/cm3 at temperature 23.33 Deg C.
Particle size distribution:
The particle size distribution of 4-(2-aminoethyl)phenol was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 150 micron to 53 micron.
Vapour pressure:
The estimated vapour pressure of 4-(2-aminoethyl) phenol at temperature 25 deg C was 0.4226 Pa
Partition coefficient:
Based on the available data in a key study from authoritative and modelling databases, the partition coefficient (log Pow) value of the substance 4 -(2 -Aminoethyl)phenol was estimated to be 0.86.
In a supportingstudy from peer reviewed journal,the partition coefficient (log Pow) value of the substance 4 -(2 -Aminoethyl)phenol was estimated to be in the range from 0.97 – 1.13, respectively.
Additional study from authoritative and modelling database indicates that the octanol waterpartition coefficient (log Pow) value of the substance 4 -(2 -Aminoethyl)phenol was estimated to be 0.72.
Another supporting study from modelling database indicates that the partition coefficient (log Pow) value of the substance 4 -(2 -aminoethyl) phenol was estimated to be 0.782 ± 0.205 at 25°C.
Thus, based on the available information, the logPow valueof the test substance 4 -(2 -Aminoethyl)phenol ranges from 0.72 to 1.13, respectively. On the basis of this estimated value, chemical 4 -(2 -Aminoethyl)phenol can be considered to be hydrophilic in nature.
Water solubility:
Water solubility of chemical 4-(2-aminoethyl) phenol is determine to be 10400 mg/L at temperature 15 Deg C. From this solubility value it is concluded that chemical 4-(2-aminoethyl) phenol is very soluble in water.
From other reliable sources & authoritative databases it is concluded that water solubility of chemical 4 -(2 -aminoethyl) phenol is determine to be 10526 mg/L at temperature 15 Deg C, 11000 mg/L at temperature 15 Deg C & 10500 mg/L at temperature 20 Deg C. From this solubility values it is concluded that chemical 4-(2-aminoethyl) phenol is very soluble in water.
Surface tension:
In accordance with column 2 of Annex VII of the REACH regulation, the study need only be conducted if surface activity is a desired property of the chemical. 4-(2-Aminoethyl)phenol (CAS no. 51-67-2) is used as a flavoring agents. For this use, surface activity is not an important property. Hence this study was considered for waiver.
Flash point:
The study does not need to be conducted because the flash point is only relevant to liquids and low melting point solids.
Auto flammability:
4-(2-aminoethyl)phenol did not catch fire on being exposed to air at room temperature of 27°Cpressure of 966 hPa. This indicates that 4-(2-aminoethyl)phenol is not auto-flammable.
Flammability:
4-(2-aminoethyl)phenol does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 4-(2-aminoethyl)phenol is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 4-(2-aminoethyl)phenol was considered non-flammable.
Explosiveness:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties.
Oxidizing properties:
The study does not need to be conducted because the substance is a solid.
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