Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Link to relevant study record(s)

bioaccumulation in aquatic species: fish
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance has a low potential for bioaccumulation based on log Kow <=3
Reason / purpose for cross-reference:
data waiving: supporting information

Description of key information

Bioaccumulation: aquatic/sediment: the constituents of the submission substance have low potential for bioaccumulation

Key value for chemical safety assessment

Additional information

The constituents of the submission substance are expected to hydrolyse moderately to rapidly to form substances which have low log Kow values (<3) and thus have low potential for bioaccumulation. In addition, the constituents of the substance have low predicted log Kow values of <3. Therefore, in accordance with Column 2 of REACH Annex IX, the bioaccumulation in aquatic species study does not need to be conducted.

A measured BCF study is available for 3-aminopropyl(triethoxy)silane (CAS 919-30-2) which hydrolyses rapidly to form 3-aminopropylsilanetriol (Silanol HP-Z) and ethanol. A steady-state BCF value of 3.4 was determined in a reliable study conducted according to an appropriate test protocol, and in compliance with GLP. The test material supplied by the sponsor was easily hydrolysed in aqueous solution forming 3-aminopropyltrihydroxysilane. Therefore, it was considered that the test organisms are exposed to the 3-aminopropyltrihydroxysilane hydrolysis product (silanol HP-Z).