Registration Dossier

Administrative data

Endpoint:
sensitisation data (humans)
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: No OECD guideline or GLP defined. Insufficient data documentation.

Data source

Reference
Reference Type:
publication
Title:
Studies on the toxicity and skin effects of compounds used in the rubber and plastics industries
Author:
Mallette F.S., von Haam E.
Year:
1952
Bibliographic source:
Arch. Hyg. Occup. Med. 6, 231-236 (1952)

Materials and methods

Type of sensitisation studied:
skin
Study type:
other: human subjects
Principles of method if other than guideline:
Sensitization toxicity in human
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Details on test material:
Santicizer 140= monotolyldiphenyl phosphate

Method

Type of population:
not specified
Controls:
no data
Route of administration:
dermal

Results and discussion

Any other information on results incl. tables

The test substance was not found to have a sensitizing effect.

Applicant's summary and conclusion

Executive summary:

In a patch test the test substance was tested in 15 -30 human subjects. Sensitation tests were performed two weeks after the primary irritation test. The test substance was not found to have a sensitizing effect.