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Sediment toxicity

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Reference
Endpoint:
sediment toxicity: long-term
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:
Justification for type of information:
Long term daphnia and sediment tests are available for 8 different cationic surfactants. The results of these studies were compared to the via EPM calculated effects as justification of the use of the EPM for cationic surfactants. For 5 out of the 8 the EPM predicted the EC10 for sediment organisms more conservatively than what was observed in the sediment test without applying the additional safety factor of 10 to compensate for ingestion. After including the additional AF (of 10), for all 8 substances the EPM was found to be more conservative than the observed sediment toxicity. The Kp sups-water for these substances ranged from 1040 L/kg to 20100 L/kg.
New data sediment and daphnia data on cationic surfactants are frequently generated and will be added to the dataset in the end to generate sufficient support using the appropriate ECHA guideline to report the respective information..
Executive summary:

Aquatic PNEC is used to calculate the benthic PNEC using a Kpsusp-sed of 3526 L/kg.

Description of key information

No benthic test data is available for N-C16-18-alkyl-(even numbered, C18 unsaturated) trimethylpropane-1,3 -diamine. The PNEC for benthic organisms is therefore calculated applying the equilibrium partitioning method using a Kpsusp-sed (or Kdsusp-sed) of 3526 L/kg

The EPM based benthic PNEC (without the correction for additional uptake via food) of 1.07 mg/kg dw

Distribution constants for for N-C16-18-alkyl-(even numbered, C18 unsaturated) trimethylpropane-1,3 -diamine as used in the calculation of the PNECsed.

 

Kpsoil

1763 L/kg

Ksoil-water

2646 m3/m3

Kpsusp

3526 L/kg

Ksusp-water

882 m3/m3

Kpsed

1763 L/kg

Ksed-water

882 m3/m3

Since PNECfreshwater is based on the bulk concentration, a recalculation was necessary to PNECfreshwaterdissolved before application of the equilibrium partitioning method. The following equation was used:

PNECfreshwaterdissolved= PNECfreshwaterbulk/ (1 + Kpsusp-sed * SUSPwater*10-6)

Where:

PNECfreshwaterbulk= 0.32 µg/L

Kpsusp-sed = 3526 L/kg

SUSPwater= 15 mg/L.

The resulting PNECfreshwaterdissolved= 0.304 µg/L.

The PNECsed is then calculated using the equations detailed in REACH guidance R.16:

                         PNECsed                         =   Ksusp-sed-water* PNECaquatic dissolved* 1000 * 1 / RHOsed

Where:         PNECaquatic-dissolved            =      0.304 µg/L

                         Ksusp-sed-water                =   882 m3/m3

                         RHOsed                          =   1150 kg/m3

                         PNECsed-EPM                 = 0.233 mg/kg ww

                                                               = 1.07 mg/kg dw

Note that an additional AF of 10 is not yet applied as this is in general automatically applied by CHESAR

                          

Long term daphnia and sediment tests are available for 8 different cationic surfactants. The results of these studies were compared to the via EPM calculated effects as justification of the use of the EPM for cationic surfactants. For 5 out of the 8 the EPM predicted the EC10 for sediment organisms more conservatively than what was observed in the sediment test without applying the additional safety factor of 10 to compensate for ingestion. After including the additional AF (of 10), for all 8 substances the EPM was found to be more conservative than the observed sediment toxicity. The Kp sups-water for these substances ranged from 1040 L/kg to 20100 L/kg.

Name CAS number Long term daphia NOEC/EC10 dissolved (µg/L) EPM data sediment Ratio observed/predicted NOEC/EC10 
Kpsusp-water (L/kg) AF for ingestion Observed Benthic NOEC/EC10 (mg/kg dw) Predicted Benthic NOEC/EC10 using the EPM (µg/L)
Amines, N-C16-18-alkyl (evennumbered) propane-1,3-diamine 133779-11-0  315.08 1040 y 86 32.88 2.62
1,3-Propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]- branched acetate 102047-27-8 87.37 4020 y 134 35.15 3.81
Quaternary ammonium compounds, C20-22-alkyltrimethyl, chlorides 68607-24-9 124.61 1813.5 y 62.5 22.64 2.76
2,2'-(octadec-9-enylimino)bisethanol 25307-17-9 9.62 7460 n 101.2 71.82 1.41
Quaternary ammonium compounds, di-C12-18-alkyldimethyl, chlorides 68391-05-9 8.55 16800 n 320 143.61 2.23
C16-18-(even numbered, C18-unsaturated)-alkylamines 68037-95-6 12.73 1394 n 188 17.80 10.56
Quaternary ammonium compounds, di-C10-alkyldimethyl, chlorides 7173-51-9 14.00 20098.8 n 530 281.43 1.88
C12-16 alkyldimethylbenzylammonium chloride 68424-85-1 4.15 16778.8 n 520 278.53 1.87

New data sediment and daphnia data on cationic surfactants are frequently generated and will be added to the dataset in the end to generate sufficient support using the appropriate ECHA guideline to report the respective information..

It should be noted that real measured sorption data are used which are not normalized to the organic matter content of the soils and that for both sediment and soil the same Kd is used. For suspended matter however the Kd is doubled to compensate for the additional sorption due to a higher content of small particles.

Key value for chemical safety assessment

Additional information

 PNECsed-EPM                 = 0.233 mg/kg ww = 1.07 mg/kg dw

Note that an additional AF of 10 is not yet applied as this is in general automatically applied by CHESAR