Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification

Data source

Reference
Reference Type:
other: prediction
Title:
Unnamed
Year:
2016

Materials and methods

Test guideline
Qualifier:
no guideline required
Principles of method if other than guideline:
QSAR

Test material

Constituent 1
Chemical structure
Reference substance name:
(8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione - 2,3,5,6-tetrachlorobenzene-1,4-diol (1:1)
EC Number:
926-987-6
Molecular formula:
C22H28O33.C6H2Cl4O2
IUPAC Name:
(8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione - 2,3,5,6-tetrachlorobenzene-1,4-diol (1:1)

Results and discussion

% Degradation
Parameter:
probability of ready biodegradability (QSAR/QSPR)
Value:
19.6
Remarks on result:
not readily biodegradable based on QSAR/QSPR prediction

Applicant's summary and conclusion

Interpretation of results:
not readily biodegradable