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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
other: Data collection
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
1982

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
- Principle of test: Acute oral toxicity test
- Short description of test conditions: The test item was oraly administered to mice. The animals were observed for clinical effects or mortality.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Aminocaproic acid
EC Number:
200-469-3
EC Name:
Aminocaproic acid
Cas Number:
60-32-2
Molecular formula:
C6H13NO2
IUPAC Name:
6-aminohexanoic acid
Test material form:
solid

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Control animals:
not specified

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LD50
Effect level:
14 300 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
In an acute oral toxicity study in mouse, a LD50 of 14300 mg/kg bw was determined.