Registration Dossier
Registration Dossier
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EC number: 609-306-4 | CAS number: 3689-69-8
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 002
- Report date:
- 2002
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- no
- Remarks:
- non-GLP screenig test
Test material
- Reference substance name:
- 6,10,14-Trimethyl-5-Pentadecen-2-on
- EC Number:
- 609-306-4
- Cas Number:
- 3689-69-8
- Molecular formula:
- C18H34O
- IUPAC Name:
- 6,10,14-Trimethyl-5-Pentadecen-2-on
- Details on test material:
- - Name of test material (as cited in study report): Tetrahydrofarnesylaceton (THFAC)
- Lot/batch No.: 01rg11
- Analytical purity: ca. 95 %, containing ca. 1,5 % Tetrahydronerolidol.
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Method: Since the test item is not well water soluble, the test substance in M4-media was stirred for about 20 hours prior to a 20 min lasting centrifugation period at 17700 g.
Test organisms
- Test organisms (species):
- other: Daphnia magna STRAUS
- Details on test organisms:
- Daphnia magna, in house culture since 1979
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Nominal and measured concentrations:
- nominal: 0, 0.01, 0.1, 1.0, 10, 100 mg/L
- Details on test conditions:
- The swimming ability of the daphnia was checked visually after 24 and 48 h of exposure: No toxic effects were observed in the range of the test concentrations tested.
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- >= 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Reported statistics and error estimates:
- Not applicable due to the abosence of any effect observed up to the highest test concentration.
Applicant's summary and conclusion
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Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
