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Key value for chemical safety assessment

Effects on fertility

Description of key information

In oral reproductive and developmental toxicity studies of cetyl betaine in rats, the LOAEL for the dams was 50 mg/kg due to decreased body weight gain and a maternal NOAEL could not be calculated. The developmental LOAEL was 250 mg/kg and the developmental NOAEL was 150 mg/kg.

Effect on fertility: via oral route
Endpoint conclusion:
no adverse effect observed

Justification for classification or non-classification

Additional information