Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
04.05. - 14.06.2000
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2000
Report date:
2000

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient - HPLC Method)
Version / remarks:
1992
Deviations:
no
GLP compliance:
yes
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
425-120-4
EC Name:
-
Cas Number:
83847-14-7
Molecular formula:
C23H23NO5
IUPAC Name:
4-cyanophenyl 4-{[6-(prop-2-enoyloxy)hexyl]oxy}benzoate
Test material form:
solid

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
4.5
Temp.:
40 °C
pH:
7

Applicant's summary and conclusion

Conclusions:
The log Pow of the test item was determined to be greater than 4.5.
Executive summary:

The partition coefficient n-octanol/water of the test substance was determined to be 4.5 according to EU Method. A.8.