Registration Dossier

Administrative data

First-aid measures

If breathed in, move person into fresh air. If symptoms persist, call a physician.

In case of skin contact take off contaminated clothing and shoes immediately. Wash off immediately with plenty of water. Call a physician immediately. Wash contaminated clothing before reuse.

In case of eye contact rinse immediately with plenty of water, also under the eyelids, for at least 5 minutes. Remove contact lenses. If eye irritation persists, consult a specialist.

If swallowed, rinse mouth with water (only if the person is conscious). Call a physician immediately.

Most important symptoms and effects, both acute and delayed
Symptoms : May cause sensitisation by skin contact.

Indication of any immediate medical attention and special treatment needed: Treat symptomatically.

Fire-fighting measures

Suitable extinguishing media: Water mist, Dry powder, Foam Carbon dioxide (CO2), Sand, Aqueous film forming foam (AFFF). Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

Unsuitable extinguishing media: Water spray jet

Special hazards arising from the substance or mixture
Specific hazards during firefighting : Risk of dust explosion.

Hazardous combustion products: Carbon oxides, Nitrogen oxides (NOx)

Advice for firefighters
Special protective equipment for firefighters: In the event of fire, wear self-contained breathing apparatus. Firefighters must wear fire resistant personal protective equipment.

Further information: In the event of fire, cool tanks with water spray. Avoid dust formation.

Accidental release measures

Personal precautions: Evacuate personnel to safe areas. Avoid breathing dust. Avoid dust formation. Keep away from open flames, hot surfaces and sources of ignition.

Environmental precautions: Should not be released into the environment. Do not flush into surface water or sanitary sewer system.

Methods for cleaning up :
Large spills: Sweep up or vacuum with HEPA filter or via wet cleaning into suitable containers for disposal. Pick up and arrange without creating dust. Keep in properly labelled containers.
Small spills: Moisten a towel, cover the spill, pick up the spill or use HEPA vacuum.
Large spills and Small spills: Keep in suitable, closed containers for disposal. Treat recovered material as described in the section "Disposal considerations".

Handling and storage

Advice on safe handling: Ensure all equipment is electrically grounded before beginning transfer operations. To avoid thermal decomposition, do not overheat. Use personal protective equipment as required. Keep away from heat and sources of ignition. Avoid inhalation, ingestion and contact with skin and eyes. Avoid formation of dust and aerosols.

Advice on protection against fire and explosion: Avoid dust formation.

Hygiene measures: Handle in accordance with good industrial hygiene and safety practice.

Dust explosion class: St2

Requirements for storage areas and containers: To maintain product quality, do not store in heat or direct sunlight. Store in original container. Keep containers tightly closed in a cool, well-ventilated place. Store at room temperature.

Recommended storage temperature: 15 - 25 °C

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:
UN 3077
Shipping information
Proper shipping name and description:
ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (1-acetyl-4-(4-hydroxyphenyl)piperazine)
Chemical name:
1-acetyl-4-(4-hydroxyphenyl)piperazine
Labels:
9
Special provisions / remarks
Special provisions:
Special Provision 375: Environmentally Hazardous Substances/Marine Pollutants, classified under UN 3077 or UN 3082, packaged in single or combination packagings containing a net quantity per single of inner packaging of 5L or less for liquids or having a net mass per single of inner packaging of 5kg or less for solids are not subject to the ADR/RID/ADN/IMDG/IATA DGR provided the packagings meet the general requirements of 4.1.1.1, 4.1.1.2, and 4.1.1.4 to 4.1.1.8.
Remarks:
Hazard Identification Number : 90
Tunnel restriction code : (-)
This substance can be shipped under 'de minimi's quantities' provisions if the net quantity per inner package <= 1mL for liquids or <= 1g for solids and the net quantity per outer package does not exceed 100mL for liquids or 100g for solids and provided packaging provisions of ADR/RID/ADN/IMDG §3.5.1.4 are met.

Inland waterway transport (UN RTDG/ADN(R))

UN number:
UN 3077
Shipping information
Proper shipping name and description:
ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (1-acetyl-4-(4-hydroxyphenyl)piperazine)
Chemical name:
1-acetyl-4-(4-hydroxyphenyl)piperazine
Labels:
9
Special provisions / remarks
Remarks:
Hazard Identification Number : 90
Special Provision 375: Environmentally Hazardous Substances/Marine Pollutants, classified under UN 3077 or UN 3082, packaged in single or combination packagings containing a net quantity per single of inner packaging of 5L or less for liquids or having a net mass per single of inner packaging of 5kg or less for solids are not subject to the ADR/RID/ADN/IMDG/IATA DGR provided the packagings meet the general requirements of 4.1.1.1, 4.1.1.2, and 4.1.1.4 to 4.1.1.8. This substance can be shipped under 'de minimi's quantities' provisions if the net quantity per inner package <= 1mL for liquids or <= 1g for solids and the net quantity per outer package does not exceed 100mL for liquids or 100g for solids and provided packaging provisions of ADR/RID/ADN/IMDG §3.5.1.4 are met.

Marine transport (UN RTDG/IMDG)

UN number:
UN 3077
Shipping information
Proper shipping name and description:
ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
(1-acetyl-4-(4-hydroxyphenyl)piperazine)
Chemical name:
1-acetyl-4-(4-hydroxyphenyl)piperazine
Labels:
9
Marine pollutant
Special provisions / remarks
Remarks:
2.10.2.7: Environmentally Hazardous Substances/Marine Pollutants, classified under UN 3077 or UN 3082, packaged in single or combination packagings containing a net quantity per single of inner packaging of 5L or less for liquids or having a net mass per single of inner packaging of 5kg or less for solids are not subject to the IMDG provided the packagings meet the general requirements of 4.1.1.1, 4.1.1.2, and 4.1.1.4 to 4.1.1.8.. This substance can be shipped under 'de minimi's quantities' provisions if the net quantity per inner package <= 1mL for liquids or <= 1g for solids and the net quantity per outer package does not exceed 100mL for liquids or 100g for solids and provided packaging provisions of ADR/RID/ADN/IMDG §3.5.1.4 are met.

Air transport (UN RTDG/ICAO/IATA)

UN number:
UN 3077
Shipping information
Proper shipping name and description:
Environmentally hazardous substance, solid, n.o.s.
(1-acetyl-4-(4-hydroxyphenyl)piperazine)
Chemical name:
1-acetyl-4-(4-hydroxyphenyl)piperazine
Labels:
9
Special provisions / remarks
Remarks:
Packing instruction (cargo aircraft): 956
Packing instruction (LQ) : Y956
Packing instruction (EQ) : E1
Remarks : Special Provision A197: Environmentally hazardous substances, classified under UN 3077 or UN 3082, when transported in single or combination packagings containing a net quantity per single or inner packaging of 5 L or less for liquids or having a net mass of 5 kg or less for solids, are not subject to any other provisions of the IATA DGR provided the packagings meet the general provisions of IATA DGR 5.0.2.4.1, 5.0.2.6.1.1 and 5.0.2.8., This substance can be shipped under 'de minimi's quantities' provisions if the net quantity per inner package <= 1mL for liquids or <= 1g for solids and the net quantity per outer package does not exceed 100mL for liquids or 100g for solids and provided packaging provisions of IATA DGR §2.6.10 are met.
SpecialProvisionsopen allclose all

Exposure controls / personal protection

Engineering controls should be used as the primary means to control possible exposures. Use process enclosures, local exhaust ventilation or other engineering controls to keep exposure levels below recommended exposure limits. All personal protective equipment should be based on a risk assessment. Consult a Environment Health Safety expert if necessary.

Eye protection: Tightly fitting safety goggles

Hand protection:
Material: Nitrile rubber
Remarks: Impervious gloves. Take note of the information given by the producer concerning permeability and break through times, and of special workplace conditions (mechanical strain, duration of contact).

Skin and body protection: Closed work clothing disposable one-piece overall with integral hood

Respiratory protection : Engineering controls should always be the primary method of controlling exposures. If respiratory protective equipment is needed for certain activities, the type as well as the corresponding protection factor will depend upon the risk assessment and air concentrations, hazards, physical and warning properties of substances present. Use only respiratory protection that conforms to international/ national standards. Suitable mask with particle filter P3

Protective measures: The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Stability and reactivity

Reactivity: None reasonably foreseeable.
Chemical stability: Stable under recommended storage conditions.
Possibility of hazardous reactions: Risk of dust explosion.
Conditions to avoid: To avoid thermal decomposition, do not overheat. Heat, flames and sparks.
Materials to avoid: Oxidizing agents
Hazardous decomposition products: Nitrogen

Disposal considerations

Waste treatment methods: Must be incinerated in a suitable incineration plant holding a permit delivered by the competent authorities. In accordance with National, Federal, State and Local regulations.

Contaminated packaging: Empty containers should be taken to an approved waste handling site for recycling or disposal.