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EC number: 947-329-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 21 Feb - 23 Feb 1995
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.2 (Acute Toxicity for Daphnia)
- GLP compliance:
- yes
- Analytical monitoring:
- yes
- Vehicle:
- no
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: water flea
- Strain: Clone 5
- Source: in-house culture
- Age at study initiation: < 24 hours
- Method of breeding: parthenogenesis in Elendt M4 medium
- Feeding during test: no
ACCLIMATION
- Acclimation period: continuous
- Type and amount of food: Scenedesmus subspicatus
- Feeding frequency: daily - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Post exposure observation period:
- not relevant
- Hardness:
- no data
- Test temperature:
- 20 ± 1 °C
- pH:
- 8.0 - 8.1 (measured at test end)
- Dissolved oxygen:
- 7.5 - 8.5 mg/L (measured at test end)
- Nominal and measured concentrations:
- nominal: 0, 90, 150, 280, 500 and 900 mg/L
measured geometric mean: 0, 45, 96, 176, 314 and 697 mg/L
Concentrations of the anionic active ingredient are given. - Details on test conditions:
- TEST SYSTEM
- Test vessel: 10 mL glasses
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 4
- No. of vessels per control (replicates): 4
- No. of vessels per reference control (replicates): 4
- Biomass loading rate: 2 mL per animal
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: synthetic freshwater
- Ca/Mg ratio: 4:1
OTHER TEST CONDITIONS
- Photoperiod: continuous dark
EFFECT PARAMETERS MEASURED: Immobilisation after 24 and 48 h. - Reference substance (positive control):
- yes
- Remarks:
- potassium dichromate
- Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- 176 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- act. ingr.
- Remarks:
- anionic active ingredient
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 483 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- act. ingr.
- Remarks:
- anionic active ingredient
- Basis for effect:
- mobility
- Remarks on result:
- other: 332-704 (95% C.L.)
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- > 697 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- act. ingr.
- Remarks:
- anionic active ingredient
- Basis for effect:
- mobility
- Details on results:
- - Behavioural abnormalities: Before complete immobilization, daphnids were observed to swim at the surface of the test vessels.
- Results with reference substance (positive control):
- - Results with reference substance valid? yes
- Mortality: 35% immobilisation at 1 mg/L potassium dichromate, 100% immobilisation at 2 mg/L potassium dichromate - Reported statistics and error estimates:
- - EC50 calculation was conducted according to Probit analysis adapted from Cavalli-Sforza (1972)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Principles of method if other than guideline:
- Method: other: AFNOR T.90301 (1974), no further information
- GLP compliance:
- no
- Analytical monitoring:
- no
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Daphnia magna Straus
- Water media type:
- freshwater
- Total exposure duration:
- 24 h
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 800 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
- Principles of method if other than guideline:
- Method: other: Norme Francaise Homologue, 1983, NF T90-31, no further information
- GLP compliance:
- no
- Analytical monitoring:
- no
- Details on test solutions:
- Distilled water solution of the surfactant was used.
- Test organisms (species):
- Daphnia magna
- Water media type:
- freshwater
- Total exposure duration:
- 24 h
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 470 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Remarks:
- Summary of available data used for the endpoint assessment of the target substance
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- Refer to the Category Approach Justification document provided in IUCLID6 Section 13.
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 483
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- act. ingr.
- Remarks:
- anoinic active ingredient
- Basis for effect:
- mobility
- Remarks on result:
- other: Source, WoE, 126-92-1, 1995
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 800 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: Source, WoE, 142-87-0, 1978
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 470 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: Source, WoE, 142-87-0, 1991
Referenceopen allclose all
Table 1: Immobilization of Daphnia magna after 24 and 48 h. The concentrations are provided as anionic active ingredient.
Measured concentration geometric mean [mg/L] |
% Immobile |
|
24 h |
48 h |
|
control |
0 |
0 |
45 |
5 |
5 |
96 |
0 |
0 |
176 |
10 |
5 |
314 |
0 |
20 |
697 |
30 |
75 |
Description of key information
48h EC50 (Daphnia magna, immobilization) > 100 mg/L
Key value for chemical safety assessment
Additional information
Since no reliable acute toxicity to aquatic invertebrates test is available for Sulfuric acids, C9-11-iso-C10 rich, alkyl esters, sodium salt, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 a read-across to other structurally related substances was conducted. As the toxicity of alkyl sulfates is dependent on the carbon chain length, it is expected that the toxic effects are comparable for the similar homologues.
One GLP study investigating short-term toxic effects of C8-isoAS Na (CAS 126-91-2) to Daphnia magna is available (Elementis, 1995). The test was performed according to EU Method C.2 under static conditions. Inhibition of mobility of daphnids caused by the test substance was determined after 24 and 48 of static exposure to five test concentrations up to 697 mg a.i./L (measured concentration equal to 900 mg a.i./L of nominal concentration). The results show that the 48-hour EC50 value was 483 mg a.i./L (measured concentration).
Moreover two 24-hour tests with Daphnia magna are available for C10AS Na (CAS 142-87-0). The first non-GLP study followed a method described by Norme Francaise Homologue, 1983, NF T90-31 (Sanchez Leal 1991). The 24-hour EC50 value was 470 mg/L. Analytical check of the test concentrations was not provided. The other non-GLP study was performed following an AFNOR T.90301 (1974) method (Lundahl and Cabridenc 1978). The obtained results showed that the 24-hour EC50 value was 800 mg/L (nominal concentrations). Analytical measurements are not available.
Due to structural and property similarities with the tested similar substances, it can be concluded that the above results apply also to Sulfuric acids, C9-11-iso-C10 rich, alkyl esters, sodium salt. The 48-hour EC50 value for aquatic invertebrates is above 100 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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