Registration Dossier
Registration Dossier
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EC number: 200-394-6 | CAS number: 58-71-9
Endpoint summary
Administrative data
Description of key information
May cause sensitization by skin contact and inhalation.
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
Many studies put in evidence that common skin reactions are urticaria, rash, exanthem, pruritus, maculopapular or morbilliform skin eruption.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
Studies show the ability of cephalosporins to cause occupational asthma. It has been suggested that the pathogenesis is mediated by Ig-E and also by non- immunologic mechanism.
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
