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Administrative data

Description of key information

Not skin sensitising

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

There are no information about the skin sensititation potential of Acid Red 336, thus the available data on structural analogous Similar Substance 03 have been taken into account (details and explanations are included in the report attached to the IUCLID section 13).

Testing for the sensitizing properties of Similar Substance 03 was performed in female guinea pigs according to the method of Burhelr, according to the OECD guideline 406. Dermal induction was performed using 100 % test item moistened with deionized water. The control group was exposed to deionized water only. Challenge treatment was carried out with 20 % test item in deionized water.

No signs of irritation were observed in the control and the treatment group 24 and 48 hours after removal of the occlusive bandage. Based on the results of the study, the substance showed no evidence for sensitizing properties.

Justification for classification or non-classification