Registration Dossier
Registration Dossier
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EC number: 236-114-4 | CAS number: 13171-00-1
Endpoint summary
Administrative data
Description of key information
In the table below the aquatic toxicity data are summarised
| Species | Guideline | Result in mg/L | Remarks |
Pseudokirchneriella subcapitata |
OECD TG 201 |
EC50 growth rate > 0.49 EC10 growth rate > 0.49 NOEC growth rate >= 0.49 Based on 0-Hour measured test concentration |
Key study, Rel 1, |
Daphnia maga |
OECD TG 202 |
EC50 48h = 0.43 Based on geometric mean measured test concentrations |
Key study, Rel 1, |
| Acartia tonsa | LC50 48h = 2.5 | See additional information | |
| Acartia tonsa | 5 -day EC50 (juvenile development) = 0.16 EC10 (juvenile development) = 0.036 |
See additional information | |
| Medaka larvae | LC50 96h = 1.97 | See additional information |
Additional information
Additional available information:
The information on Daphnia magna is leading for hazard and classification and labelling being the lowest value. The information presented below on the marine species and fish is included to complete the available information on Celestolide and has no effect on classification and labelling.
Marine copepods (Acartia tonsa) acute test
A 48-hour acute toxicity test was conducted on marine copepods (Acartia tonsa) with a method that is scientifically valid and somewhat in line with OECD TG 202 using nominal concentrations (Wollenberger, 2003, Kl.2) presenting LC50 = 2.5 mg/L. The concentrations tested were 0.063 - 2.0 mg/L. The LC50 was extrapolated outside this tested range and is above the water solubility and therefore difficult to interpret.
Marine copepods (Acartia tonsa) more long-term test
A larval development test was performed using marine copepods (Acartia tonsa) with a method presenting some limitations because nominal concentrations were used and partly renewal of the medium on day 3 (Wollenberger, 2003). The 5-day EC50 (juvenile development) value = 0.16 mg/L. The EC10 (juvenile development) = 0.036 mg/L. Tested concentration range was 0.015-1.5 mg/L.
Fish acute toxicity test
An acute fish toxicity test (no guideline used) using 24-h-old medaka larvae gives a 96-h LC50 value of 1.97 (1.87–2.08) mg/L.
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