1-chloro-2,3-epoxypropane

Guidance on Safe Use

First-aid measures

· General information:

Immediately remove any clothing soiled by the product.

Remove breathing equipment only after contaminated clothing have been completely removed.

In case of irregular breathing or respiratory arrest provide artificial respiration.

Take note of the following instructions:

· After inhalation:

Supply fresh air or oxygen; call for doctor.

In case of unconsciousness place patient stably in the recovery position for transportation.

· After skin contact:

Immediately wash with water and soap and rinse thoroughly.

Remove contaminated clothing immediately.

Seek immediate medical advice.

· After eye contact:

Rinse opened eye for several minutes under running water. Then consult a doctor.

· After swallowing: Do not induce vomiting; call for medical help immediately.

· Most important symptoms and effects, both acute and delayed

No further relevant information available.

· Indication of any immediate medical attention and special treatment needed

No further relevant information available

Fire-fighting measures

· Extinguishing media

· Suitable extinguishing agents: CO2, sand, extinguishing powder. Do not use water.

· For safety reasons unsuitable extinguishing agents: Water

· Special hazards arising from the substance or mixture

Can form explosive gas-air mixtures.

Carbon monoxide and carbon dioxide

During heating or in case of fire poisonous gases are produced.

· Advice for firefighters

· Protective equipment:

Wear self-contained respiratory protective device.

Wear personal protective equipment.

· Additional information

Cool endangered container(s) with water spray.

Dispose of fire debris and contaminated fire fighting water in accordance with official regulations.

Heating of container(s) will cause pressure rise with risk of bursting and subsequent explosion (BLEVE).

Accidental release measures

· Personal precautions, protective equipment and emergency procedures

Wear personal protective equipment. Keep unprotected persons away.

Mount respiratory protective device.

Remove persons from danger area.

Ensure adequate ventilation.

· Environmental precautions:

Do not allow to enter sewers/ surface or ground water.

Suppress gases/fumes/haze with water spray.

· 6.3 Methods and material for containment and cleaning up:

Ensure adequate ventilation.

Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).

Clean the affected area carefully; suitable cleaners are:

water

Dispose contaminated material as waste according to specifications.

Handling and storage

· Precautions for safe handling

Ensure good ventilation/exhaustion at the workplace.

Open and handle receptacle with care.

Prevent formation of aerosols.

Ensure good interior ventilation, especially at floor level. (Fumes are heavier than air).

Prevent static electric sparks.

· Information about fire - and explosion protection:

Keep ignition sources away - Do not smoke.

Protect against electrostatic charges.

Keep respiratory protective device available.

Protect from heat.

Fumes can combine with air to form an explosive mixture.

When heated the product forms flammable fumes.

Heating of container(s) will cause pressure rise with risk of bursting and subsequent explosion (BLEVE).

The vapour may be invisible and is heavier than air. It spreads along the ground and may enter sewers and basements.

· Conditions for safe storage, including any incompatibilities

· Storage:

· Requirements to be met by storerooms and receptacles:

Store in a cool location.

Provide solvent resistant, sealed floor.

· Information about storage in one common storage facility:

Do not store together with acids.

Do not store together with alkalis (caustic solutions).

Store away from foodstuffs.

Store away from oxidising agents.

· Further information about storage conditions:

Keep container tightly sealed.

Protect from heat and direct sunlight.

Open receptacle only under localised extractor facilities.

Store under lock and key and with access restricted to technical experts or their assistants only.

Store in a cool place. Heat will increase pressure and may lead to the receptacle bursting.

· 7.3 Specific end use(s): No further relevant information available.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

UN 2023

Shipping information

Proper shipping name and description:

2023 EPICHLOROHYDRIN

Labels:

6.1+3

Special provisions / remarks

Remarks:

Excepted quantities (EQ): E2
· Limited quantities (LQ): 100 ml
· Excepted quantities (EQ) Code: E4
Maximum net quantity per inner packaging: 1 ml
Maximum net quantity per outer packaging: 500 ml
· Transport category: 2
· Tunnel restriction code: D/E

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

UN number:

UN 2023

Shipping information

Proper shipping name and description:

EPICHLOROHYDRIN

Labels:

6.1/3

Special provisions / remarks

Remarks:

· Limited quantities (LQ): 100 ml
· Excepted quantities (EQ) Code: E4
Maximum net quantity per inner packaging: 1 ml
Maximum net quantity per outer packaging: 500 ml

Air transport (UN RTDG/ICAO/IATA)

UN number:

UN 2023

Shipping information

Proper shipping name and description:

EPICHLOROHYDRIN

Labels:

6.1 (3)

Special provisions / remarks

Remarks:

UN No. 2032
Special provisions: A113
Danger Code: 6F
UN packing group: II
PASSENGER AND CARGO AIRCRAFT:
Excepted Quantities: E4
Packing instruction: 654
max. net quantity per package: 5 L
Limited Quantity:
Packing instruction: Y641
max. net quantity per package: 1 L
CARGO AIRCRAFT:
Packing instruction: 662
max. net quantity per package: 60 L
GRACE recommends CARGO AIRCRAFT only.

Additional transport information

Additional information

Special provisions / remarks / other:

· Environmental hazards: Not applicable.

· Special precautions for user Warning: Toxic substances.
· Danger code (Kemler): 63
· EMS Number: F-E,S-D
· Stowage Category: A
· Stowage Code: SW2 Clear of living quarters.

· Transport in bulk according to Annex II of Marpol and the IBC Code: Not applicable.

Exposure controls / personal protection

· Ingredients with limit values that require monitoring at the workplace:

106-89-8 1-chloro-2,3-epoxypropane

WEL (Great Britain) Short-term value: 5.8 mg/m³, 1.5 ppm

Long-term value: 1.9 mg/m³, 0.5 ppm

Carc

· DNEL (106-89-8 1-chloro-2,3-epoxypropane)

Inhalative DNEL(long-systemic) 1.52 mg/m³ (Worker); ECHA 2016

DNEL(long-local) 1.52 mg/m³ (Worker); ECHA 2016

· PNECs (106-89-8 1-chloro-2,3-epoxypropane)

57 mg/kg (aqua-freshwater); ECHA 2016

6 mg/kg (aqua-marine water); ECHA 2016

5 mg/kg (soil); ECHA 2016

11 mg/l (aqua-freshwater); ECHA 2016

106 mg/l (aqua-intermittent releases); ECHA 2016

1 mg/l (aqua-marine water); ECHA 2016

35 mg/l (Sewage Treatment Plant); ECHA 2016

· Additional information: Valid lists at time of creation were used as basis.

· Exposure controls

· Personal protective equipment:

· General protective and hygienic measures:

Keep away from foodstuffs, beverages and feed.

Immediately remove all soiled and contaminated clothing.

Wash hands before breaks and at the end of work.

Store protective clothing separately.

Avoid contact with the eyes and skin.

· Respiratory protection:

In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use self-contained respiratory protective device.

· Recommended filter device for short term use: Filter AX

· Protection of hands:

Protective gloves.

Check the condition of the gloves prior to each use.

The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.

Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation.

Preventive skin protection by use of skin-protecting agents is recommended.

· Material of gloves

The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer.

Butyl rubber, BR

Recommended thickness of the material: >= 0.7 mm

· Penetration time of glove material

EN 420: Minimum requirements for efficiency level 1 for all groups.

The exact break through time has to be obtained from the manufacturer of the protective gloves and has to be observed.

For the mixture of chemicals mentioned below the penetration time has to be at least 480 minutes (Permeation according to EN 374 Part 3: Level 6).

· For the permanent contact gloves made of the following materials are suitable:

Butyl rubber, BR

· Not suitable are gloves made of the following materials:

Leather gloves

cloth gloves

· Eye protection:

Tightly sealed goggles

· Body protection: Protective work clothing.

Stability and reactivity

· Reactivity: No further relevant information available.

· Chemical stability

No decomposition if used according to specifications.

No decomposition if used and stored according to specifications.

· Possibility of hazardous reactions

Forms explosive gas mixture with air.

Violent reactions with strong alkalis and oxidising agents.

· Conditions to avoid

In case of thermal decomposition caused by smouldering and incomplete combustion toxic fumes may be developed.

· Incompatible materials: Protect from contamination.

· Hazardous decomposition products:

Poisonous gases/vapours

Carbon monoxide and carbon dioxide

Disposal considerations

· Waste treatment methods

· Recommendation: Disposal must be made according to official regulations.

· Waste disposal key:

The disposal of the product has to be carried out in accordance with the legal requirements. EWC waste codes are strictly industry-oriented, therefore waste classification has to be done by the waste producer.

· Uncleaned packaging:

· Recommendation: Disposal must be made according to official regulations.