Registration Dossier
Registration Dossier
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EC number: 256-907-9 | CAS number: 51012-32-9
Endpoint summary
Administrative data
Description of key information
The substance is predicted to have a LD50 of ca. 717 mg/kg bw.
Key value for chemical safety assessment
Acute toxicity: via oral route
Link to relevant study records
- Endpoint:
- acute toxicity: oral
- Type of information:
- (Q)SAR
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: ECHA guidance on information requirements and chemical safety assessment Chapter R.6: QSARs and grouping of chemicals.
- Species:
- rat
- Statistics:
- The applicability domain of predictions is assessed considering:
- Similar molecules with known experimental value.
- Accuracy of prediction for similar molecules.
- Concordance for similar molecules. - Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- ca. 717 mg/kg bw
- Interpretation of results:
- Category 4 based on GHS criteria
- Conclusions:
- The substance has a LD50 of ca. 717 mg/kg bw.
Reference
The result appears reliable as the predicted compound is into the applicability domain of the model.
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 717 mg/kg bw
- Quality of whole database:
- No experimental data are available. The database includes a QSAR prediction showing a good reliability. Overall, the quality of the whole database is limited.
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
Overall, data are deemed to be inconclusive for classification.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
