Registration Dossier
Registration Dossier
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EC number: 277-962-5 | CAS number: 74665-14-8
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (48 h) > 100.0 mg test item/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- EC50
- Effect concentration:
- > 100 mg/L
Additional information
This study was performed to assess the toxic effects of phenol sulphonated (EC: 277-962-5; CAS: 74665-14-8) sold under the commercial name SELLATAN P to Daphnia magna,
under static conditions.
Based on the results of the preliminary range-finding study, the main study was restricted to the limit study, and it was performed at test concentration level of 100.0 mg/L. In the limit study, 48 h toxicity test procedure was followed, comprising two groups (one control and treatment). Each group consisted of four replicates containing 5 daphnids per replicate.
The stability test of test item in test media was performed during the method validation (JRF Study N° 228-
2-13-32625). Test item in the test media was found stable up to 48 h (>80% of the nominal concentration).
Test media was analysed for concentration and stability at 0 and 48 h during the limit study and was within the acceptable limit (>80% of the nominal concentration). Therefore, results are expressed in nominal concentration.
The highest tested concentration level of test item causing no immobilisation was 100.0 mg test item/L.
There was no immobility or adverse sub-lethal behavioural responses observed up to 48 h at the highest tested concentration. Therefore, 48 h EC50 could not be calculated and is estimated to be greater than 100.0 mg test item/L.
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