Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 807-380-4 | CAS number: 377734-55-9
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Reported 19Jan2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Deviations:
- not specified
- GLP compliance:
- no
- Other quality assurance:
- other: ISO9001
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- 7-hydroxy-N,N,N-trimethylnaphthalen-2-aminium methyl sulfate
- Cas Number:
- 377734-55-9
- Molecular formula:
- C14H19NO5S
- IUPAC Name:
- 7-hydroxy-N,N,N-trimethylnaphthalen-2-aminium methyl sulfate
- Test material form:
- solid: particulate/powder
Constituent 1
- Specific details on test material used for the study:
- NBTRI
RK0400 16-09-01 (Spray Dried)
Study design
- Analytical method:
- photometric method
Results and discussion
Partition coefficient
- Key result
- Type:
- Pow
- Partition coefficient:
- 0.018
- Temp.:
- 20 °C
- pH:
- 7
- Details on results:
- In a separating funnel 100ml of distilled water was added followed by 100 ml of octan-1-ol, this was
then shaken and left to settle for 10 minutes. 0.4823g of sample was added to the separating funnel,
this was shaken for 1 minute. The solution was then left overnight to allow the 2 phases to separate.
The next day the phases were separated into 2 100 ml volumetric flasks. These solutions were then
measured on the spectrophotometer using the relevant solvent as a blank.
Abs in octan-1-ol 0.544088@ 330 nm
Abs in water 1.49172 @330 nm (20 fold dilution required to get the abs in range)
0.544088 / 29.8344 = 1.8×10-2
Applicant's summary and conclusion
- Conclusions:
- The Pow was experimentally determined to be 0.018 in a lab with a constant temperature of 20°C.
- Executive summary:
The Pow was experimentally determined to be 0.018 in a lab with a constant temperature of 20°C.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
