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EC number: 220-378-2 | CAS number: 2744-49-2
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.1 (Acute Toxicity for Fish)
- GLP compliance:
- not specified
- Vehicle:
- yes
- Details on test solutions:
- Ethanol
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- TEST ORGANISM
- Common name: zebrafish - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 96 h
- Nominal and measured concentrations:
- 500 mg/l
- Details on test conditions:
- TEST SYSTEM
- No. of vessels per concentration: 1 replicate with only test item.
- No. of vessels per control: 1 replicate.
- No. of vessels per vehicle control: 1 replicate with test item solubilized in ethanol. - Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 500 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- At 500 mg/l, with and without 100 mg/l of ethanol as solubilizers, no effects were found. The indicated concentrations refer to the introduced and not to the dissolved amount of substance.
- Conclusions:
- LC50 (96h) > 500 mg/l (nominal)
- Executive summary:
The acute lethal toxicity of test item to zebrafish was investigated under static exposure conditions, over a period of 96 h. The test was conducted according to the OECD guideline 203. The applied nominal test concentration was 500 mg/l. One replicates was tested with test item solubilized in ethanol and one replicate was tested including test item only.
At 500 mg/l, with and without 100 mg/l of ethanol as solubilizers, no effects were found.
Conclusion
LC50 (96h) > 500 mg/l (nominal)
Reference
Description of key information
LC50 (96h) > 500 mg/l (nominal)
Key value for chemical safety assessment
Additional information
The acute lethal toxicity of test item to zebrafish was investigated under static exposure conditions, over a period of 96 h. The test was conducted according to the OECD guideline 203. The applied nominal test concentration was 500 mg/l. One replicates was tested with test item solubilized in ethanol and one replicate was tested including test item only. At 500 mg/l, with and without 100 mg/l of ethanol as solubilizers, no effects were found.
Unfortunately, the complete study report cannot be retrieved, thus details about test conditions are not available.
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