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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
Qualifier:
according to guideline
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
Qualifier:
according to guideline
Guideline:
EU Method C.1 (Acute Toxicity for Fish)
GLP compliance:
not specified
Vehicle:
yes
Details on test solutions:
Ethanol
Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)
Details on test organisms:
TEST ORGANISM
- Common name: zebrafish
Test type:
static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
96 h
Nominal and measured concentrations:
500 mg/l
Details on test conditions:
TEST SYSTEM
- No. of vessels per concentration: 1 replicate with only test item.
- No. of vessels per control: 1 replicate.
- No. of vessels per vehicle control: 1 replicate with test item solubilized in ethanol.
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
> 500 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Details on results:
At 500 mg/l, with and without 100 mg/l of ethanol as solubilizers, no effects were found. The indicated concentrations refer to the introduced and not to the dissolved amount of substance.
Conclusions:
LC50 (96h) > 500 mg/l (nominal)
Executive summary:

The acute lethal toxicity of test item to zebrafish was investigated under static exposure conditions, over a period of 96 h. The test was conducted according to the OECD guideline 203. The applied nominal test concentration was 500 mg/l. One replicates was tested with test item solubilized in ethanol and one replicate was tested including test item only.

At 500 mg/l, with and without 100 mg/l of ethanol as solubilizers, no effects were found.

Conclusion

LC50 (96h) > 500 mg/l (nominal)

Description of key information

LC50 (96h) > 500 mg/l (nominal)

Key value for chemical safety assessment

Additional information

The acute lethal toxicity of test item to zebrafish was investigated under static exposure conditions, over a period of 96 h. The test was conducted according to the OECD guideline 203. The applied nominal test concentration was 500 mg/l. One replicates was tested with test item solubilized in ethanol and one replicate was tested including test item only. At 500 mg/l, with and without 100 mg/l of ethanol as solubilizers, no effects were found.

Unfortunately, the complete study report cannot be retrieved, thus details about test conditions are not available.