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Boiling point

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Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
28 February - 01 March 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
The study was conducted according to an internationally recognised method, and under GLP. The test substance is adequately characterised. Therefore full validation applies.
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling Point)
Version / remarks:
1995
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
Version / remarks:
2008
Deviations:
no
Principles of method if other than guideline:
Not applicable
GLP compliance:
yes (incl. QA statement)
Remarks:
Inspected on 4,5 and 6 July 2016/ Signed on 10 January 2017
Type of method:
differential scanning calorimetry
Key result
Boiling pt.:
300.1 °C
Atm. press.:
101.3 kPa
Decomposition:
yes
Decomp. temp.:
189.6 °C

First determination:(atmospheric pressure: 953 hPa)

An exothermic peak was observed at 189.5 °C (onset temperature of the first peak) and corresponds to the degradation of the substance.

Initial boiling point under decomposition was observed at 297 °C (onset temperature of the first peak) and a corresponding mass loss was observed on the TG curve, showing that all the substance was evaporated at the end of the study.

The crucible was visually checked after the determination: By opening the crucible, no test item left in the crucible.

Second determination: (atmospheric pressure: 946 hPa)

An exothermic peak was observed at 189.7 °C (onset temperature of the first peak) and corresponds to the degradation of the substance.

Initial boiling point under decomposition was observed at 297 °C (onset temperature of the first peak) and a corresponding mass loss was observed on the TG curve, showing that all the substance was evaporated at the end of the study.

The crucible was visually checked after the determination: By opening the crucible, no test item left in the crucible

In case of small pressure deviations the boiling temperature at standard pressure can be calculated following the equation of Sidney-Young.

Tn= T + (ƒ x ∆p)

With

Tn  = boiling point at 101.325 kPa in K

T    = measured boiling point in K

ƒ    = correction factor (tabulated value)

∆p  = (101.325 – p) kPa

P   = measured atmospheric pressure in kPa

The corrected values following Sidney-Young equation has been determined to be 300.1 °C at 101.3 kPa (mean of 300.0 °C for the first determination and 300.3 °C for the second determination).

 

In addition, an exothermic peak was observed at 189.6°C (mean of 189.5 °C for the first determination and 189.7 °C for the second determination) and corresponds to the degradation of the substance. For this reason, the initial boiling point obtained has to be considered for the degraded substance.

Conclusions:
Initial boiling point under decomposition of test item has been determined to be 300.1 °C at 101.3 kPa (mean of 300.0 °C for the first determination and 300.3 °C for the second determination).
An exothermic peak was observed at 189.6°C (mean of 189.5 °C for the first determination and 189.7 °C for the second determination) and corresponds to the degradation of the substance. For this reason, the initial boiling point obtained has to be considered for the degraded substance.
Executive summary:

The study was performed in order to determine the boiling point of test item according to OECD 103, resp. EU A.2, using the DSC method.

Initial boiling point under decomposition of test item has been determined to be 300.1 °C at 101.3 kPa (mean of 300.0 °C for the first determination and 300.3 °C for the second determination).

Description of key information

The initial boiling point under decomposition of the substance was determined as 300.1°C at 101.3kPa.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
300.1 °C

Additional information

A fully reliable experimental study, conducted according to OECD 103/ EU A2 guideline is available.

It is considered as a key study, and the result is retained as key data.