Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Water solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
February from 12 to 16, 2018
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Reason / purpose for cross-reference:
reference to other study
validated anaytical method
according to guideline
OECD Guideline 105 (Water Solubility)
Version / remarks:
adopted July 27, 1995
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Water solubility:
325 g/L
Conc. based on:
test mat.
20 °C
ca. 8.12
Details on results:
The measured concentrations resulted to be constant within ± 15 % and, thus, within the range required by the guidelines.

The solubility of the test item was higher than 10 mg/l (351 g/l), therefore the flask method was used for the main test.

Sampling time  Measured concentration of test item (g/l) Measured pH
test vessels mean with the 95 % confidence intervals
After 24h 327 325 ± 22.8 8.12
314 8.11
332 8.13
After 48h 327 331 ± 11.9 8.12
330 8.12
336 8.12
After 72h 320 321 ± 2.1 8.14
321 8.14
320 8.13
Solubility of the test item (g/l) 325 ± 13.0 8.12
RSD% 2 -
pH of ultra-pure water - 6.38
Water solubility: 325 ± 13 g/l at 20 °C and pH ca 8.12
Executive summary:

The water solubility of the substance was determined following method and procedures outlined into the OECD guideline 105. In the course of the study, the water solubility of test item was determined at 20 ± 0.5 °C using the flask method for the performance of the main test. The substance was dissolved in water at a temperature somewhat above the test temperature. When saturation was achieved the mixture was cooled and kept at the test temperature, stirring as long as necessary to reach equilibrium. Subsequently, the mass concentration of the substance in the aqueous solution, which must not contain any undissolved particles, was determined by a suitable analytical method, previously validated.

The water solubility resulted to be 325 ± 13 g/l (95 % confidence interval), at 20 °C and pH ca 8.12.


Water solubility: 325 ± 13 g/l at 20 °C and pH ca 8.12

Description of key information

325 ± 13 g/l at 20 °C and pH ca 8.12

Key value for chemical safety assessment

Water solubility:
325 g/L
at the temperature of:
20 °C

Additional information

OECD 105 - flask method