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EC number: 923-900-3 | CAS number: -
An Acute Dermal Irritation/Corrosion Test according to OECD TG 404 was conducted with the test substance. Under the conditions of the test no signs of irritation could be observed at all after 24, 48 and 72 hours postexposure-time. There were no systemic intolerance reactions.
Substances are classified as „corrosive (R34)“, if the cell viability of the EST 1000 is decreased by more than 50 % after 3 min. of incubation to the test item, or if the cell viability is less than 15 % after 60 min. of exposure to the test item.
control NaCl 0.9 %
The test substance was characterized by no significant impact on cell viability after 3 min. or after the 60 min. period.
An Acute Eye Irritation/ Corrosion Test according to OECD TG 405 was conducted with the test substance. Under the conditions of the test only slight effects were observed (3/3 rabbits showed conjunctivae score 1 or 2 after 24 hours, fully reversed at least after 72 hours). There were no systemic intolerance reactions.
The test substance was not irritating to the skin of rabbits in a study conducted according to OECD TG 404. It was slightly irritating to the eye of rabbits in a study according to OECD TG 405 (3/3 animals showed score 1 to 2 for conjunctivae (redness) after 24 h, fully reversed after 72 h).
No classification is required for skin or eye irritation/corrosion according to Regulation (EC) No 1272/2008, Annex I.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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