Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Endpoint summary

Administrative data

Description of key information

4,4,7,7-Tetraethoxy-3,8-dioxa-4,7-disiladecane is a liquid at standard temperature and pressure, with a measured melting point of -34°C and a measured boiling point of 267.7°C. It has a measured relative density of 0.966 at 20°C and a measured vapour pressure values of 0.3 Pa at 20°C and 6.3 Pa at 50°C.


The substance is not classified as a flammable liquid according to Regulation (EC) No. 1272/2008 on the basis of a measured flash point of 116.5°C and a measured boiling point of 267.7°C. It has a measured auto-ignition temperature of 228°C at 969 -979 hPa and is not explosive and not oxidising on the basis of structural examination.


In contact with water, 4,4,7,7-tetraethoxy-3,8-dioxa-4,7-disiladecane reacts moderately (half-life of 36 hours at pH 7, 0.8 hours at pH 4, 0.7 hours at pH 5 and 0.5 hours at pH 9 and 20-25°C) to produce 1,1,1,4,4,4-hexahydroxy-1,4-silabutane and ethanol according to the following equation:

C14H34O6Si2+ 6H2O → C2H10O6Si2 + 6C2H6O


The key physicochemical properties of the parent submission substance have been predicted using a validated QSAR estimation method. 4,4,7,7 -Tetraethoxy-3,8-dioxa-4,7-disiladecane has a predicted log Kow value of 2.7 at 20°C and predicted water solubility value of 20 mg/L at 20°C.

The saturation concentration in water of the silanol hydrolysis product, 1,1,1,4,4,4-hexahydroxy-1,4-silabutane, is limited by condensation reactions to approximately 100-500 mg/l. However, it is very hydrophilic (calculated solubility is 1E+06 mg/l at 20°C using a QSAR method), has a predicted log Kow value of -4.0 and it has a predicted vapour pressure of 4.4E-0.8 Pa at 25°C.

Ethanol has a reported log Kow of -0.3, vapour pressure of 7910 Pa at 25°C and is miscible with water.

Additional information