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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

short-term toxicity to aquatic invertebrates
Type of information:
Adequacy of study:
key study
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
no guideline available
Principles of method if other than guideline:
Toxicity Estimation Software Toolkit (TEST) v4.2
QPRF and QMRF reports are attached in IUCLID
GLP compliance:
Specific details on test material used for the study:
SMILES: O=C[C@H]([C@H]([C@@H]([C@H](O)CO)O)O)O
Key result
48 h
Dose descriptor:
Effect conc.:
9 523.24 mg/L
Validity criteria fulfilled:
48-hr LC50 (Daphnia magna): 9523.24 mg/L
Executive summary:

The Consensus model for acute aquatic toxicity to Daphnia was used within the Toxicity Estimation Software Toolkit (TEST). The model predicts a 48-hour LC50 value of 9523.24 mg/L in Daphnia. Additional supporting documentation is provided in the prediction report attached in IUCLID.

Description of key information

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
9 523 mg/L

Additional information