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Administrative data

Endpoint:
appearance / physical state / colour
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: observation made during recent water solubility testing
Cross-reference
Reason / purpose for cross-reference:
reference to same study
Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2016-12-22 to 2016-12-30
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
1995
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
2008
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Key result
Water solubility:
37.2 g/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
8.58

- Preliminary Test:

Approximate solubility was above 10 mg/L.

- Main Test:

In flask 1 2.496 g was weighed in 10 mL water, and in flask 2 2.2502 g in 10 mL water.

Results of the water solubility of test item: 

Time of

shaking

[h]

Analyte concentration

Flask 1

Analyte concentration

Flask 2

mean concentration

[g/L]

pH value

25

36.4

37.0

36.7

8.56

49

36.6

37.3

37.0

8.58

70

38.3

37.3

37.8

8.61

 

Mean:

37.2

8.58

Standard deviation:

0.6

0.03

Relative standard deviation[%):

1.6

0.3

The results indicate the required reproducibility (relative standard deviation below 15 %) and no tendency to increasing values, when the shaking time was prolonged.

Conclusions:
The water solubility of the test item in ultra-pure water saturated with carbon dioxide at 20 ± 0.5°C was determined to be 37.2 g/L (pH 8.58).
Executive summary:

The solubility of test item was determined in ultra-pure water in equilibrium with atmospheric carbon dioxide at a temperature of 20±0.5 °C according to EC method A.6 (Regulation (EC) No 440/2008) and OECD guideline 105. The shake flask method was used, because the solubility determined in the preliminary test was above 10 mg/L.

The water solubility of the test item was determined to be 37.2 g/L (pH 8.58).

The results indicate the required reproducibility (relative standard deviation below 15 %) and no tendency to increasing values, when the shaking time was prolonged.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
no guideline followed, the results are obtained from observations made during a recent study water solubility of the substance.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Bis[N-(2-hydroxyethyl)-N-methylglycinato-N,O,ON]copper
EC Number:
300-491-4
EC Name:
Bis[N-(2-hydroxyethyl)-N-methylglycinato-N,O,ON]copper
Cas Number:
93940-93-3
Molecular formula:
C10H20CuN2O6
IUPAC Name:
bis[N-(2-hydroxyethyl)-N-methylglycinato-N,O,ON]copper
Test material form:
solid: particulate/powder

Results and discussion

Physical state at 20°C and 1013 hPa:
solid
Form / colour / odour
Key result
Form:
solid
Colour:
blue
Substance type:
organic

Applicant's summary and conclusion

Conclusions:
The test substance is a blue solid product.
Executive summary:

The results are obtained from observations made during a recent study on water solubility testing of the substance. The substance is a blue solid product.