Registration Dossier
Registration Dossier
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EC number: 240-040-8 | CAS number: 15901-40-3
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A 48-hour EC50 value of 36.3 mg/l (nominal concentration) in unbuffered media has been determined for the effects of cyclohexylamine on mobilisation of Daphnia magna.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 36.3 mg/L
Additional information
A 48-hour EC50 value of 36.3 mg/l (nominal concentration) in unbuffered media has been determined for the effects of cyclohexylamine on mobilisation of Daphnia magna in compliance with OECD Test Guideline 202 (Daphnia sp. Acute Immobilisation Test) (data from ECHA registration dossier, review article or handbook, MITI 1997).
The addition of test material can cause a shift in pH in unbuffered media. pH values of individual concentration levels increased from 7.4 (5.3 mg/L) up to 10.1 (100.0 mg/L). pH values over time did not vary more than 1.5 units except in the 100 mg/L test concentration, where all Daphnia were immobilised within 24 hours. There is, therefore, uncertainty over the cause of the effects in this top concentration.
However, as the EC50 value is well below the 100 mg/l concentration, the uncertainty with regards to pH effects in this concentration may not have had a significant effect on the overall results.
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