Registration Dossier

Diss Factsheets

Administrative data

Link to relevant study record(s)

basic toxicokinetics, other
Toxicokinetic assumption
Type of information:
other: Toxicokinetic assumption
Adequacy of study:
weight of evidence
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Toxicokinetic assumption
Objective of study:
other: Toxicokinetic assumption
Principles of method if other than guideline:
Toxicokinetic assumption
GLP compliance:

Description of key information

The data from the acute oral and repeated dose toxicity studies indicate no or a low absorption by the oral route based on the acute oral LD50 > 15000 mg/kg bw and the NOAEL of 1000 mg/kg bw in the Repeated Dose 28 Day Oral Toxicity Study in Rodents and the Combined Repeated Dose Toxicity Study with the Reproduction / Developmental Toxicity Screening Test).

Key value for chemical safety assessment

Bioaccumulation potential:
low bioaccumulation potential

Additional information