Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 208-728-2 | CAS number: 539-88-8
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (72h) = 932.1 mg/l (measured)
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 932.1 mg/L
Additional information
The toxic potential of the substance to aquatic algae was evaluated following a method based on the OECD 201 Guideline. Selenastrum capricornutum were exposed to 7 concentrations of the substance ranging from 50.692 mg/l to 8602.17 mg/l for 72 hours. Four replicates of the substance and of the negative control which run in parallel were tested. The growth rate inhibition and the EC50 was determined based on the cell concentration measured. The concentrations of the test substance as well as the pH of the test solution and negative control were measured at 0 h and at 72 h.
EC50 (72h) = 932.1 mg/l (measured); EC50 (72h) = 1171 mg/l (nominal)
Data from a literature study supports the evaluation of the toxic potential of the substance. The toxicity potential of the substance to green algae was evaluated after 2 hours of exposure to different concentrations of the substance (ranging from 0 -22000 mg/l). Fluorescence parameters were measured on 2 ml algal suspension after 1 and 2 h of exposure.
EC50 (2h) = 6065.9 ± 757.8 mg/l
For the chemical safety assessement the key study result is chosen as it derives from a test conducted following a method based on the OECD Guideline 201. In addition, the exposure duration is the exposure period suggested by the OECD 201 Guideline and the effect concentration is lower. The test item concentrations were monitored and there are more details considering the testing procedure. Considering the aforementioned, EC50 (72h) = 932.1 mg/l is used as a key value. The NOEC and/or the EC10 was not determined in the study.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
